Schmitt, Lukas; Schaub, Michael; Kriegel, Martin (2021)
TGA-Kongress, 28.-29.01.2021 in Berlin / Online.
DOI: 10.13140/RG.2.2.34007.34726
Coelho, Vitor Lima; Fontenele de Brito, Tarcísio; Alexandre de Abreu Brito, Ingrid; Arruda Cardoso, Maira; Berni, Mateus Antonio; Araujo, Helena Maria Marcolla; Sammeth, Michael; Pane, Attilio (2021)
Coelho, Vitor Lima; Fontenele de Brito, Tarcísio; Alexandre de Abreu Brito, Ingrid...
Scientific Reports 2021, 1918 (11).
DOI: 10.1038/s41598-021-81387-1
Rhodnius prolixus is a Triatominae insect species and a primary vector of Chagas disease. The genome of R. prolixus has been recently sequenced and partially assembled, but few transcriptome analyses have been performed to date. In this study, we describe the stage-specific transcriptomes obtained from previtellogenic stages of oogenesis and from mature eggs. By analyzing ~ 228 million paired-end RNA-Seq reads, we significantly improved the current genome annotations for 9206 genes. We provide extended 5' and 3' UTRs, complete Open Reading Frames, and alternative transcript variants. Strikingly, using a combination of genome-guided and de novo transcriptome assembly we found more than two thousand novel genes, thus increasing the number of genes in R. prolixus from 15,738 to 17,864. We used the improved transcriptome to investigate stage-specific gene expression profiles during R. prolixus oogenesis. Our data reveal that 11,127 genes are expressed in the early previtellogenic stage of oogenesis and their transcripts are deposited in the developing egg including key factors regulating germline development, genome integrity, and the maternal-zygotic transition. In addition, GO term analyses show that transcripts encoding components of the steroid hormone receptor pathway, cytoskeleton, and intracellular signaling are abundant in the mature eggs, where they likely control early embryonic development upon fertilization. Our results significantly improve the R. prolixus genome and transcriptome and provide novel insight into oogenesis and early embryogenesis in this medically relevant insect.
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko; Sirios , F. (2021)
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko...
Arthritis Care & Research, n/a(n/a).
DOI: 10.1002/acr.24440
Toussaint, L.; Nguyen, Q. A.; Roettger, C.; Dixon, K.; Offenbächer, M.; Kohls, Niko; Hirsch, Jameson; Sirois, F. (2021)
Toussaint, L.; Nguyen, Q. A.; Roettger, C.; Dixon, K.; Offenbächer, M.; Kohls, Niko...
in Promoting Psychological and Physiological States of Relaxation. Evidence-based Complementary and Alternative Medicine, 2021, 5924040. doi:10.1155/2021/5924040.
Bottino-Leone, Dario; Larcher, Marco; Troi, Alexandra; Grunewald, John (2021)
Construction and Building Materials 266.
DOI: 10.1016/j.conbuildmat.2020.121497
Zagel, Christian (2021)
Multisensorik im stationären Handel - Grundlagen und Praxis der kundenzentrierten Filialgestaltung 2021, S. 221-235.
DOI: 10.1007/978-3-658-31273-2
Wenzel, M.; Rauch, M.; Abiodun Adegbile, A.; Bogodistov, Y.; Cénophat, S.; Hartmann, Michael; Wagner, D.; Wohlgemuth , V. (2021)
Wenzel, M.; Rauch, M.; Abiodun Adegbile, A.; Bogodistov, Y.; Cénophat, S....
Dynamic Capabilities and Relationships: Discourses, Concepts, and Reflections 2021, S. 5-41.
DOI: 10.1007/978-3-030-83182-0_1
Zagel, Christian; Hasenkopf , Hauke ; Hoffmann, Mark (2021)
Hochschule Coburg .
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko; Sirois, F. M. (2021)
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko...
Arthritis Care & Research 2021 73 (1), S. 55–64.
DOI: 10.1002/acr.24440
OBJECTIVE
Offenbächer, M.; Kohls, Niko; Ewert, T.; Sigl, C.; Hieblinger, R.; Toussaint, L. L.; Sirois, F. M.; Hirsch, J. K.; Vallejo, M. A.; Kramer, S.; Rivera, J.; Stucki, G.; Schelling, J.; Winkelmann, A. (2021)
Offenbächer, M.; Kohls, Niko; Ewert, T.; Sigl, C.; Hieblinger, R.; Toussaint, L. L....
Rheumatology International 2021.
DOI: 10.1007/s00296-020-04702-5
OBJECTIVE
Holtorf, Christian (2021)
Ergebnisse interdisziplinärer Lehre Band 2 2021.
Kohls, Niko (2020)
Health Promotion & Physical Activity, 2020, 4 (13), 62-64.
Appel, Alexandra; Scheiner, Joachim; Wilde, Mathias (2020)
Vogt, Irmgard; Bischof, Gallus; Hannak-Zeltner, Renate; Hößelbarth, Susann; Jückstock, Julia; Hoffmann, Sabine (2020)
Vogt, Irmgard; Bischof, Gallus; Hannak-Zeltner, Renate; Hößelbarth, Susann...
Vogt, I., Bischof, G.; Hannak-Zeltner, R.; Hößelbarth, S.; Jückstock, J. & Hoffmann, S. (2020). 3.7.2 Schwangere/ Frauen ab 18 Jahren / Frauen als Angehörige. In: Deutsche Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde (DGPPN) & Deutsche Gesellschaft für Suchtforschung und Suchttherapie e.V. (DG-SUCHT) (Hrsg.). S3 Leitlinie „Screening, Diagnose und Behandlung alkoholbezogener Störungen”. Version Dezember 2020 (S. 270-312). Verfügbar unter: https://www.awmf.org/leitlinien/detail /ll/076-001.html. [27.04.2022], S. 270-312.
Hamberger, Jens; Hinterberger , Thilo ; Loew, T.; Meißner, Karin; Weimer, K. (2020)
e-Poster beim Kongress der Deutschen Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde (DGPPN), 26.11.2020, Online-Kongress.
Markert, Michael (2020)
Dissertation, Bauhaus-Universität Weimar, 2020.
DOI: 10.25643/bauhaus-universitaet.4303
DiEuliis, D.; Kohls, Niko; Giordano, J. (2020)
In M. Woesler & H. M. Sass (Eds.), Medizin und Ethik in Zeiten von Corona (pp. 323 - 327), S. 323-327.
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Kohls, Niko; Toussaint, L.; Sirios , F. ; Untner, J.; Hirsch, J. K. (2020)
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Kohls, Niko; Toussaint, L....
Eingereicht Österreichischer Kongress für Rheumatologie 2020..
Altier, H.; Offenbaecher, M.; van der Zee-Neuen, A.; Toussaint, L.; Kohls, Niko; Hanshans, Christian ; Sirios , F. ; Untner, J.; Hölzl, B.; Gaisberger, M.; Hirsch, J. K. (2020)
Altier, H.; Offenbaecher, M.; van der Zee-Neuen, A.; Toussaint, L.; Kohls, Niko...
Eingereicht Österreichischer Kongress für Rheumatologie 2020..
DOI: 10.13140/RG.2.2.23795.81443
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A.; Lunzer, R.; Herold, Manfred; Untner, J.; Kohls, Niko; Hölzl, B.; Gaisberger, M.; Touissant, L. (2020)
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A....
Eingereicht Österreichischer Kongress für Rheumatologie 2020..
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