Pain is not the major determinant of quality of life in fibromyalgia: results from a retrospective “real world” data analysis of fibromyalgia patients
Offenbaecher, M.; Kohls, Niko; Ewert, T.; Sigl, C.; Hieblinger, R.; Toussaint, L.; Sirois, F.; Hirsch, Jameson; Vallejo, M. A.; Kramer, S.; Rivera, J.; Stucki, G.; Schelling, J.; Winkelmann, A. (2021)
Offenbaecher, M.; Kohls, Niko; Ewert, T.; Sigl, C.; Hieblinger, R.; Toussaint, L....
Rheumatology International.
DOI: https://doi.org10.1007/s00296-020-04702-5
Peer Reviewed
Die KI als Chauffeur – Zukünfte des autonomen Fahrens
Wilde, Mathias (2021)
IM+io - Das Magazin für Innovation, Organisation und Management (03), 76-79.
Patientenerwartungen bei Inanspruchnahme der multimodalen Schmerztherapie
Meißner, Karin; Gaber, Helena; Gallasch, Svenja; Grabenbauer, Andrea; Güttler, Carina; Jank, Celine; Ott, Michaela; Middeldorf, Stefan (2021)
Meißner, Karin; Gaber, Helena; Gallasch, Svenja; Grabenbauer, Andrea; Güttler, Carina...
Orthopädische und Unfallchirurgische Praxis (OUP) 10 (2), 0133–0138.
DOI: 10.3238/oup.2021.0133–0138
Open Access
Effect of thermospermine on expression profiling of different gene using massive analysis of cDNA ends (MACE) and vascular maintenance in Arabidopsis
Sagor, G; Simm, Stefan; Kim, Dong; Niitsu, Masaru; Kusano, Tomonobu; Berberich, Thomas (2021)
Sagor, G; Simm, Stefan; Kim, Dong; Niitsu, Masaru; Kusano, Tomonobu...
Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology 27 (3), 577–586.
DOI: 10.1007/s12298-021-00967-7
Open Access Peer Reviewed
Arabidopsis thaliana polyamine oxidase 5 gene (AtPAO5) functions as a thermospermine (T-Spm) oxidase. Aerial growth of its knock-out mutant (Atpao5-2) was significantly repressed by low dose(s) of T-Spm but not by other polyamines. To figure out the underlying mechanism, massive analysis of 3’-cDNA ends was performed. Low dose of T-Spm treatment modulates more than two fold expression 1,398 genes in WT compared to 3186 genes in Atpao5-2. Cell wall, lipid and secondary metabolisms were dramatically affected in low dose T-Spm-treated Atpao5-2, in comparison to other pathways such as TCA cycle-, amino acid- metabolisms and photosynthesis. The cell wall pectin metabolism, cell wall proteins and degradation process were highly modulated. Intriguingly Fe-deficiency responsive genes and drought stress-induced genes were also up-regulated, suggesting the importance of thermospermi’ne flux on regulation of gene network. Histological observation showed that the vascular system of the joint part between stem and leaves was structurally dissociated, indicating its involvement in vascular maintenance. Endogenous increase in T-Spm and reduction in H2O2 contents were found in mutant grown in T-Spm containing media. The results indicate that T-Spm homeostasis by a fine tuned balance of its synthesis and catabolism is important for maintaining gene regulation network and the vascular system in plants.
Integration of Energy-Efficient Ventilation Systems in Historic Buildings—Review and Proposal of a Systematic Intervention Approach
Rieser, Alexander; Pfluger, Rainer; Troi, Alexandra; Herrera-Avellanosa, Daniel; Engel und Thomsen, Kirsten; Rose, Jorgen; Arsan, Zeynep Durmus; Akkurt, Gulden Gokcen; Kopeinig, Gerhard; Guyot, Gaelle; Chung, Daniel (2021)
Rieser, Alexander; Pfluger, Rainer; Troi, Alexandra; Herrera-Avellanosa, Daniel...
Sustainability, 13(4), 2325. MDPI AG 2021.
DOI: 10.3390/su13042325
Open Access Peer Reviewed
Generating Homogeneous Gas Mixtures by Using Acoustic Waves
Krempel, Sandro; Seidel, N.; Tietze, Sabrina; Drese, Klaus Stefan (2021)
ACTUATOR; International Conference and Exhibition on New Actuator Systems and Applications 2021.
Ship Propulsion by Means of Acoustic Radiation
Backer, Alexander; Krempel, Sandro; Ritter, Frank; Tietze, Sabrina; Drese, Klaus Stefan (2021)
Backer, Alexander; Krempel, Sandro; Ritter, Frank; Tietze, Sabrina...
ACTUATOR, International Conference and Exhibition on New Actuator Systems and Applications 2021, Online 2021, 66 - 69.
Nowadays in almost all cases, the propulsion of ships is generated by mechanically moved propellers, which causes water flow and thrust. The disadvantage of this technology is the wear of the mechanical moving parts as well as the danger of the rotating parts in the water for example for living beings. The only alternative is still the sail or wind power.
In our approach the propulsion of a boat is generated without moving parts by means of ultrasonic waves emitted into
the water. In contrast to already existing experiments in which surface acoustic waves are conducted directly into the
water on piezoelectric substrates in order to generate a thrust, here the sound input takes place by piezoelectric transducers attached to the backside of non-piezoelectric material at the outer hull of the boat. A 3D printed model boat was
built and tested. In contrast to the previously published literature, the used electronic components and their operation for
the propulsion of the boat are described in detail. Sound generation and propagation are simulated in COMSOL
Transformation
Weinmann, Natalie (2021)
Hybride Intervention 2.
Sensorik zur Regelung von reaktionsschnellen Wärmeübergabesystemen
Schmitt, Lukas; Schaub, Michael; Kriegel, Martin (2021)
TGA-Kongress, 28.-29.01.2021 in Berlin / Online.
DOI: 10.13140/RG.2.2.34007.34726
Open Access
Analysis of ovarian transcriptomes reveals thousands of novel genes in the insect vector Rhodnius prolixus
Coelho, Vitor Lima; Fontenele de Brito, Tarcísio; Alexandre de Abreu Brito, Ingrid; Arruda Cardoso, Maira; Berni, Mateus Antonio; Araujo, Helena Maria Marcolla; Sammeth, Michael; Pane, Attilio (2021)
Coelho, Vitor Lima; Fontenele de Brito, Tarcísio; Alexandre de Abreu Brito, Ingrid...
Scientific Reports 2021 (11), 1918.
DOI: 10.1038/s41598-021-81387-1
Open Access Peer Reviewed
Rhodnius prolixus is a Triatominae insect species and a primary vector of Chagas disease. The genome of R. prolixus has been recently sequenced and partially assembled, but few transcriptome analyses have been performed to date. In this study, we describe the stage-specific transcriptomes obtained from previtellogenic stages of oogenesis and from mature eggs. By analyzing ~ 228 million paired-end RNA-Seq reads, we significantly improved the current genome annotations for 9206 genes. We provide extended 5' and 3' UTRs, complete Open Reading Frames, and alternative transcript variants. Strikingly, using a combination of genome-guided and de novo transcriptome assembly we found more than two thousand novel genes, thus increasing the number of genes in R. prolixus from 15,738 to 17,864. We used the improved transcriptome to investigate stage-specific gene expression profiles during R. prolixus oogenesis. Our data reveal that 11,127 genes are expressed in the early previtellogenic stage of oogenesis and their transcripts are deposited in the developing egg including key factors regulating germline development, genome integrity, and the maternal-zygotic transition. In addition, GO term analyses show that transcripts encoding components of the steroid hormone receptor pathway, cytoskeleton, and intracellular signaling are abundant in the mature eggs, where they likely control early embryonic development upon fertilization. Our results significantly improve the R. prolixus genome and transcriptome and provide novel insight into oogenesis and early embryogenesis in this medically relevant insect.
Positive Psychological Factors and Impairment in Rheumatic and Musculoskeletal Disease: Do Psychopathology and Sleep Quality Explain the Linkage?
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko; Sirios , F. (2021)
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko...
Arthritis Care & Research, n/a(n/a).
DOI: 10.1002/acr.24440
Peer Reviewed
Effectiveness of Progressive Muscle Relaxation, Deep Breathing, and Guided Imagery
Toussaint, L.; Nguyen, Q. A.; Roettger, C.; Dixon, K.; Offenbächer, M.; Kohls, Niko; Hirsch, Jameson; Sirois, F. (2021)
Toussaint, L.; Nguyen, Q. A.; Roettger, C.; Dixon, K.; Offenbächer, M.; Kohls, Niko...
in Promoting Psychological and Physiological States of Relaxation. Evidence-based Complementary and Alternative Medicine, 2021, 5924040. doi:10.1155/2021/5924040.
Peer Reviewed
Hygrothermal characterization of a fictitious homogenized porous material to describe multiphase heat and moisture transport in massive historic walls
Bottino-Leone, Dario; Larcher, Marco; Troi, Alexandra; Grunewald, John (2021)
Construction and Building Materials 266.
DOI: 10.1016/j.conbuildmat.2020.121497
Peer Reviewed
Consumer Experience durch Einsatz von Mixed Reality in Einkaufsumgebungen
Zagel, Christian (2021)
Multisensorik im stationären Handel - Grundlagen und Praxis der kundenzentrierten Filialgestaltung 2021, 221-235.
DOI: 10.1007/978-3-658-31273-2
Dynamic Capabilities: Celebrating the Plurality of Understandings of the Concept
Wenzel, M.; Rauch, M.; Abiodun Adegbile, A.; Bogodistov, Y.; Cénophat, S.; Hartmann, Michael; Wagner, D.; Wohlgemuth , V. (2021)
Wenzel, M.; Rauch, M.; Abiodun Adegbile, A.; Bogodistov, Y.; Cénophat, S....
Dynamic Capabilities and Relationships: Discourses, Concepts, and Reflections 2021, 5-41.
DOI: 10.1007/978-3-030-83182-0_1
Open Access
Menschenrechte verteidigen. Perspektivwechsel für Solidarität und Inklusion
Lohrenscheit , Claudia (2021)
Achour, Sabine/Gill, Thomas (Hg.): Politische Bildung und Flucht – ein Paradigmenwechsel?!, Frankfurt/Main 2021, 57-65.
ZukunftsDesign - Ein Studiengang der Regionalentwicklung
Zagel, Christian; Hasenkopf , Hauke ; Hoffmann, Mark (2021)
Hochschule Coburg .
Open Access
Positive Psychological Factors and Impairment in Rheumatic and Musculoskeletal Disease: Do Psychopathology and Sleep Quality Explain the Linkage?
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko; Sirois, F. M. (2021)
Hirsch, J. K.; Altier, H.; Offenbächer, M.; Toussaint, L.; Kohls, Niko...
Arthritis Care & Research 2021 73 (1), 55–64.
DOI: 10.1002/acr.24440
Peer Reviewed
OBJECTIVE
Pain is not the major determinant of quality of life in fibromyalgia - results from a retrospective "real world" data analysis of fibromyalgia patients
Offenbächer, M.; Kohls, Niko; Ewert, T.; Sigl, C.; Hieblinger, R.; Toussaint, L.; Sirois, F. M.; Hirsch, J. K.; Vallejo, M. A.; Kramer, S.; Rivera, J.; Stucki, G.; Schelling, J.; Winkelmann, A. (2021)
Offenbächer, M.; Kohls, Niko; Ewert, T.; Sigl, C.; Hieblinger, R.; Toussaint, L....
Rheumatology International 2021.
DOI: 10.1007/s00296-020-04702-5
Peer Reviewed
OBJECTIVE
Sportstadt Coburg. Ideen für die Regionalentwicklung
Holtorf, Christian (2021)
Ergebnisse interdisziplinärer Lehre Band 2 2021.
Open Access
Referat Forschungs- und Drittmittelservice (FDS)
Hochschule Coburg
Friedrich-Streib-Str. 2
96450 Coburg
Support of publications
Monika SchnabelForschungsreferentin, EU-Referentin
T +49 9561 317 8062
monika.schnabel[at]hs-coburg.de