Kann Architektur krank machen? Gesundheit braucht Ästhetik
Heinrich, Michael; Kohls, Niko (2024)
Podcast Hochschule Coburg.
Multi-Pedestrian Tracking and Map-based Intention Estimation for Autonomous Driving Scenario
Dehghani, Ali; Patiño Studencki, Lucila (2024)
10th. International Conference on Vehicle Technology and Intelligent Transport Systems (VEHITS) 2024.
Peer Reviewed
Tempel der Gelehrsamkeit: Die Hochschulbibliothek
Heinrich, Michael (2024)
Psychologie Heute, 5/2024 5/2024 (5).
Die neue Wärmepumpen-Generation – Teil 1: Kältemittel, Effizienz und Bauweise
Schaub, Michael (2024)
HLH 75 (05), 22-25.
DOI: 10.37544/1436-5103-2024-05-22
Gesundheitstag für Lehrkräfte
Kohls, Niko (2024)
Organisation.
Second Workshop on AI for AI Education (AI4AILearning)
Kohlhase, Michael; Leidner, Jochen L.; Schmid, Ute; Wolter, Diedrich (2024)
held at KI 2024: 47. Deutsche Jahrestagung für Künstliche Intelligenz, Würzburg, 23.09. - 27.09.2024.
Peer Reviewed
International Social Work and Social Movements
Lohrenscheit , Claudia ; Schmelz, Andrea ; Schmitt, Caroline; Straub, Ute (2024)
International Social Work and Social Movements 2024.
Peer Reviewed
Utopias for a Good Life for All People
Lohrenscheit , Claudia ; Schmelz, Andrea ; Schmitt, Caroline; Straub, Ute (2024)
International Social Work and Social Movements, 7-19.
Peer Reviewed
Outlook: Making Conditions Dance
Lohrenscheit , Claudia ; Schmelz, Andrea ; Schmitt, Caroline; Straub, Ute (2024)
International Social Work and Social Movements , 205-211.
Peer Reviewed
Die neue Wärmepumpen-Generation: Propan oder R32?
Schaub, Michael (2024)
7. Internationale Fachtagung Bauphysik & Gebäudetechnik (BGT 2024), Friedrichshafen, 365-375.
Multidimensional AI-based Health-Assistant
Blümlein, Markus; Leidner, Jochen L. (2024)
Poster, presented at Networking for Research – German Universities of Applied Sciences and Researchers from Scotland (UDIF-HAW), DFG (German Research Foundation) and SULSA (Scottish Universities Life Sciences Alliances), online, 2024-04-24.
Analytical and Numerical Analysis of the De Haller Criterion for Low-Pressure Axial Fans
Epple, Philipp; Fritsche, Manuel (2024)
Symposium on Innovative Simulations in Turbomachinery ISimT München.
Spaces to heal: Using the psychological impact of architecture
Vollmer, Tanja C.; Koppen, Gemma (2024)
Book: Rising Oceans & Spaces that Care , 109–112.
Peer Reviewed
Gesunde Architektur im bezahlbaren Wohnbau [Healthy architecture in affordable housing]
Koppen, Gemma; Vollmer, Tanja C.; Hesselschwerdt, Pia (2024)
DW Die Wohnungswirtschaft (03), 77 | 38–41.
Integrating tumor and healthy epithelium in a micro-physiology multi-compartment approach to study renal cell carcinoma pathophysiology
Somova, Maryna; Simm, Stefan; Padmyastuti, Adventina; Ehrhardt, Jens; Schoon, Janosch; Wolff, Ingmar; Burchardt, Martin; Roennau, Cindy; Pinto, Pedro Caetano (2024)
Somova, Maryna; Simm, Stefan; Padmyastuti, Adventina; Ehrhardt, Jens; Schoon, Janosch...
Scientific Reports 2024 / 14 (1), 9357.
DOI: 10.1038/s41598-024-60164-w
Open Access Peer Reviewed
The advent of micro-physiological systems (MPS) in biomedical research
has enabled the introduction of more complex and relevant physiological
into in vitro models. The recreation of complex morphological features
in three-dimensional environments can recapitulate otherwise absent
dynamic interactions in conventional models. In this study we developed
an advanced in vitro Renal Cell Carcinoma (RCC) that mimics the
interplay between healthy and malignant renal tissue. Based on the
TissUse Humimic platform our model combines healthy renal proximal
tubule epithelial cells (RPTEC) and RCC. Co-culturing reconstructed
RPTEC tubules with RCC spheroids in a closed micro-perfused circuit
resulted in significant phenotypical changes to the tubules. Expression
of immune factors revealed that interleukin-8 (IL-8) and tumor necrosis
factor-alfa (TNF-α) were upregulated in the non-malignant cells while
neutrophil gelatinase-associated lipocalin (NGAL) was downregulated in
both RCC and RPTEC. Metabolic analysis showed that RCC prompted a shift
in the energy production of RPTEC tubules, inducing glycolysis, in a
metabolic adaptation that likely supports RCC growth and immunogenicity.
In contrast, RCC maintained stable metabolic activity, emphasizing
their resilience to external factors. RNA-seq and biological process
analysis of primary RTPTEC tubules demonstrated that the 3D tubular
architecture and MPS conditions reverted cells to a predominant
oxidative phosphorylate state, a departure from the glycolytic
metabolism observed in 2D culture. This dynamic RCC co-culture model,
approximates the physiology of healthy renal tubules to that of RCC,
providing new insights into tumor-host interactions. Our approach can
show that an RCC-MPS can expand the complexity and scope of
pathophysiology and biomarker studies in kidney cancer research.
Mehr Lebensfreude durch Achtsamkeit und Resilienz
Kohls, Niko (2024)
Vortrag.
Green Office als Organisation für ein Nachhaltigkeits-Monitoring in der Region
Peer Reviewed
Wissenschaftlich belegt: 7 Strategien boostern Ihr mentales Immunsystem
Kohls, Niko (2024)
https://www.focus.de/experts/weniger-stress-mehr-gelassenheit-staerken-sie-ihr-mentales-immunsystem-experten-tipps-fuer-mehr-resilienz_id_259863156.html?utm_medium=social&utm_source=linkedin&utm_campaign=ec-livemail.
TAME II: A Modern Geographic Text Annotation Tool
Leidner, Jochen L.; Jung, Luca (2024)
Proceedings of the 21st International Symposium on Web and Wireless Geographical Information Systems (W2GIS 2024), June, 17-18, 2024, Yverdon-les-Bains, Switzerland
, 95-104.
DOI: 10.1007/978-3-031-60796-7_7
Peer Reviewed
New European Bauhaus (NEB) Living Lab Energy. Die Bedeutung der Ästhetik für das Gelingen der Energiewende
Heinrich, Michael (2024)
Keynote-Vorträge und Expertenbetreuung der Projektgruppe zur wiss. Ästhetik, New European Bauhaus (NEB) Living Lab Energy. Bayern Innovativ/ Bayr. Wirtschaftsministerium.
Referat Forschungs- und Drittmittelservice (FDS)
Hochschule Coburg
Friedrich-Streib-Str. 2
96450 Coburg
Support of publications
Jakob HankeForschungsreferent
T +49 9561 317 360
jakob.hanke[at]hs-coburg.de