Hammer, Veronika; Holtorf, Christian (2015)
Coburg 2015.
Hammer, Veronika; Holtorf, Christian (2015)
Kompetenz in Bildung. Die Hochschule in der Bildungsregion Coburg, Hochschule Coburg, , 23-25.
Holtorf, Christian (2015)
in: Safia Azzouni/Stefan Böschen/Carsten Reinhardt (Hg.): Erzählung und Geltung. Wissenschaft zwischen Autorschaft und Autorität. Weilerswist: Velbrück Wissenschaft, 133-155.
Lohrenscheit , Claudia (2015)
Peacebuilding – Gender – Social Work. International Human Rights Dialogue: Celebrating the 100th Anniversary of the Women’s Peace Congress; Paulo Freire Verlag, Oldenburg 2015 (280 Seiten), 208-218.
Lohrenscheit , Claudia (2015)
Huhle, N./ Huhle T.: Die subversive Kraft der Menschenrechte: Rainer Huhle zum radikalen Jubiläum. Paulo Freire Verlag, Oldenburg 2015, 185-196.
Lohrenscheit , Claudia (2015)
Böhm, O./Katheder, D. (Hg.): Grundkurs Menschenrechte. Die 30 Artikel. Kommentare und Anregungen für die politische Bildung. Nürnberg 2015, 116-131.
Reißing, Ralf (2015)
Workshop Studentische Ausbildung und Weiterbildung in Anforderungsspezifikationen (SAGWAS), Oktober 2015, Cottbus. In: Cunningham, D.; Hofstedt, P.; Meer, K.; Schmitt, I. (Hrsg.): Informatik 2015. Lecture Notes in Informatics (LNI), Gesellschaft für Informatik, , 623-624.
Sauer, S.; Lemke, J.; Zinn, W.; Büttner, R.; Kohls, Niko (2015)
Personality and Individual Differences 81, 117-123..
DOI: 10.1016/j.paid.2014.09.011
Vogel , B.; Karmann, C. ; Mehring , M. ; Schneider, A.; Offenbächer, M.; Kohls, Niko; Schelling, J. (2015)
Vogel , B.; Karmann, C. ; Mehring , M. ; Schneider, A.; Offenbächer, M.; Kohls, Niko...
Bio-Algorithms and Med-Systems.
DOI: 10.1515/bams-2015-0006
Hammer, Veronika; Holtorf, Christian (2015)
DCT: Coburg .
Blechschmidt, Andreas; Lanzendorf, Martin; Wilde, Mathias (2015)
Raumforschung und Raumordnung 73 (6), 423-437.
DOI: 10.1007/s13147-015-0372-5
Wilde, Mathias (2015)
Standort - Zeitschrift für Angewandte Geographie 39 (1), 22-25.
DOI: 10.1007/s00548-015-0364-2
Wilde, Mathias (2015)
Handbuch der kommunalen Verkehrsplanung: für die Praxis in Stadt und Region.
Wilde, Mathias; Gather, Matthias (2015)
Gebiets- und Verwaltungsstrukturen im Umbruch: Beiträge zur Reformdiskussion aus Erfahrungen in Sachsen, Sachsen-Anhalt und Thüringen (Arbeitsmaterial der ARL) 360, Akademie für Raumforschung und Landesplanung.
Simm, Stefan; Keller, Mario; Selymesi, Mario; Schleiff, Enrico (2015)
Frontiers in Microbiology 6, 219.
DOI: 10.3389/fmicb.2015.00219
Cyanobacteria are photosynthetic prokaryotes important for many ecosystems with a high potential for biotechnological usage e.g., in the production of bioactive molecules. Either asks for a deep understanding of the functionality of cyanobacteria and their interaction with the environment. This in part can be inferred from the analysis of their genomes or proteomes. Today, many cyanobacterial genomes have been sequenced and annotated. This information can be used to identify biological pathways present in all cyanobacteria as proteins involved in such processes are encoded by a so called core-genome. However, beside identification of fundamental processes, genes specific for certain cyanobacterial features can be identified by a holistic genome analysis as well. We identified 559 genes that define the core-genome of 58 analyzed cyanobacteria, as well as three genes likely to be signature genes for thermophilic and 57 genes likely to be signature genes for heterocyst-forming cyanobacteria. To get insights into cyanobacterial systems for the interaction with the environment we also inspected the diversity of the outer membrane proteome with focus on β-barrel proteins. We observed that most of the transporting outer membrane β-barrel proteins are not globally conserved in the cyanobacterial phylum. In turn, the occurrence of β-barrel proteins shows high strain specificity. The core set of outer membrane proteins globally conserved in cyanobacteria comprises three proteins only, namely the outer membrane β-barrel assembly protein Omp85, the lipid A transfer protein LptD, and an OprB-type porin. Thus, we conclude that cyanobacteria have developed individual strategies for the interaction with the environment, while other intracellular processes like the regulation of the protein homeostasis are globally conserved.
Simm, Stefan; Fragkostefanakis, Sotirios; Paul, Puneet; Keller, Mario; Einloft, Jens; Scharf, Klaus-Dieter; Schleiff, Enrico (2015)
Simm, Stefan; Fragkostefanakis, Sotirios; Paul, Puneet; Keller, Mario; Einloft, Jens...
Bioinformatics and Biology Insights 9, 1–17.
DOI: 10.4137/BBI.S20751
Ribosome biogenesis involves a large inventory of proteinaceous and RNA cofactors. More than 250 ribosome biogenesis factors (RBFs) have been described in yeast. These factors are involved in multiple aspects like rRNA processing, folding, and modification as well as in ribosomal protein (RP) assembly. Considering the importance of RBFs for particular developmental processes, we examined the complexity of RBF and RP (co-)orthologs by bioinformatic assignment in 14 different plant species and expression profiling in the model crop Solanum lycopersicum. Assigning (co-)orthologs to each RBF revealed that at least 25% of all predicted RBFs are encoded by more than one gene. At first we realized that the occurrence of multiple RBF co-orthologs is not globally correlated to the existence of multiple RP co-orthologs. The transcript abundance of genes coding for predicted RBFs and RPs in leaves and anthers of S. lycopersicum was determined by next generation sequencing (NGS). In combination with existing expression profiles, we can conclude that co-orthologs of RBFs by large account for a preferential function in different tissue or at distinct developmental stages. This notion is supported by the differential expression of selected RBFs during male gametophyte development. In addition, co-regulated clusters of RBF and RP coding genes have been observed. The relevance of these results is discussed.
Sloan, Katherine; Leisegang, Matthias; Doebele, Carmen; Ramírez, Ana; Simm, Stefan; Safferthal, Charlotta; Kretschmer, Jens; Schorge, Tobias; Markoutsa, Stavroula; Haag, Sara; Karas, Michael; Ebersberger, Ingo; Schleiff, Enrico; Watkins, Nicholas; Bohnsack, Markus (2015)
Sloan, Katherine; Leisegang, Matthias; Doebele, Carmen; Ramírez, Ana; Simm, Stefan...
Nucleic Acids Research 43 (1), 553–564.
DOI: 10.1093/nar/gku1291
Translation fidelity and efficiency require multiple ribosomal (r)RNA modifications that are mostly mediated by small nucleolar (sno)RNPs during ribosome production. Overlapping basepairing of snoRNAs with pre-rRNAs often necessitates sequential and efficient association and dissociation of the snoRNPs, however, how such hierarchy is established has remained unknown so far. Here, we identify several late-acting snoRNAs that bind pre-40S particles in human cells and show that their association and function in pre-40S complexes is regulated by the RNA helicase DDX21. We map DDX21 crosslinking sites on pre-rRNAs and show their overlap with the basepairing sites of the affected snoRNAs. While DDX21 activity is required for recruitment of the late-acting snoRNAs SNORD56 and SNORD68, earlier snoRNAs are not affected by DDX21 depletion. Together, these observations provide an understanding of the timing and ordered hierarchy of snoRNP action in pre-40S maturation and reveal a novel mode of regulation of snoRNP function by an RNA helicase in human cells.
Funke, Susanne A.; Birkmann, Eva; Willbold, Dieter (2014)
Advances in Alzheimer's Research
2.
DOI: 10.2174/9781608058525114020013
Markert, Michael; Geelhaar, Jens (2014)
MobileHCI '14: Proceedings of the 16th International Conference on Human-Computer Interaction with Mobile Devices and Services 16, 609-611.
DOI: 10.1145/2628363.2645700
Tamdjidi, C.; Kohls, Niko (2014)
Gesundheitswesen, 76(08/09), A196. doi: 10.1055/s-0034-1387046.
DOI: https://doi.org:10.1055/s-0034-1387046