Late ribosomal protein localization in Arabidopsis thaliana differs to that in Saccharomyces cerevisiae
Palm, Denise; Streit, Deniz; Ruprecht, Maike; Simm, Stefan; Scharf, Christian; Schleiff, Enrico (2018)
Palm, Denise; Streit, Deniz; Ruprecht, Maike; Simm, Stefan; Scharf, Christian...
FEBS open bio 8 (9), 1437–1444.
DOI: 10.1002/2211-5463.12487
Open Access Peer Reviewed
Ribosome biogenesis is essential for cellular function and involves rRNA synthesis, rRNA processing and modification, and ribosomal protein assembly. Ribosome biogenesis factors and small nucleolar RNA assist these events. Ribosomal maturation takes place in the nucleolus, the nucleoplasm, and the cytosol in a coordinated and controlled manner. For example, some ribosomal proteins are thought to be assembled in the cytoplasm based on the observations in Saccharomyces cerevisiae. Here, we used cellular fractionation to demonstrate that cleavage of the 20S intermediate, the precursor to mature 18S rRNA, does not occur in the nucleoplasm of Arabidopsis thaliana. It most likely occurs in the cytoplasm. Further, we verified the proposed localization of RPS10e, RPS26e, and RPL24a/b in the nucleus and RPP1 in the nucleolus of A. thaliana by ribosome profiling, immunofluorescence, and analysis of the localization of GFP fusion proteins. Our results suggest that the order of events during ribosomal protein assembly in the ribosome biogenesis pathway differs between plants and yeast.
Data transmission by guided acoustic waves
Ritter, Frank; Krempel, Sandro; Tietze, Sabrina; Backer, Alexander; Wolfschmitt, A.; Drese, Klaus Stefan (2018)
Ritter, Frank; Krempel, Sandro; Tietze, Sabrina; Backer, Alexander; Wolfschmitt, A....
Sensors and Measuring Systems; 19th ITG/GMA-Symposium, Nuremberg 2018, 602 - 605.
Conventional data transmission via cable or electromagnetic waves reaches their limits in harsh or hard-to-reach environments. For example in bore hole inspection, cables can break and electromagnetic waves cannot pass different earth layers. Actual studies showing that guided waves are a possible instrument for cable less data transmission. The known technique works with frequencies below 100 kHz for a wave propagating of long distances and known time delays. This concept limits the data transmission rate to e.g. 250 bit/s at a 2m long steel pipe. Other cable less developments are also known in so-called "wall to wall" communication by means of ultrasonic sound waves. Here, frequencies of 1 MHz are used to transmit data in the order of 550 bit/s through one wall with opposing transducers. In our approach we are using guided waves with a center frequency of 1 MHz. Furthermore a sweep mode is used instead of the pulse position modulation (PPM). Thus, it is possible to be independent of a known transmitter and receiver position and thereby the knowledge of the time delay. Thereby, in contrast to the already known technology it is possible to use a two-dimensional arbitrary surface for data communication. At a first experiment, a data transmission distance of 20 cm at a 3 mm glass plate was build. One single-phase transducer is used as transmitter and two different transducers as receiver to show the independence of position of the receiver. Wave reflections at the edges of the glass plate and dispersion of the guided wave could also be eliminated by the here used algorithm of identifying the biggest amplitude of the received signal. Thereby a transmission rate of 1,5 kBit/s with good SNR could be observed.
Entspannungs-Apps im BGM–Einsatzmöglichkeiten und Implementierung
Nagel, Andreas; Kohls, Niko; John, D. (2018)
In D. Matusiewicz & L. Kaiser (Eds.). Digitales Betriebliches Gesundheitsmanagement (pp. 347-357). Wiesbaden: Springer Gabler., 347-357.
Salutogenese gemeinsam und interdisziplinär weiterdenken – Erfahrungen aus und mit dem Studiengang Integrative Gesundheitsförderung Coburg
Röhrich, Christina; Kraft, Jana; Nagel, Andreas; Kohls, Niko (2018)
Der Mensch, 56(1), 41-45.
The coupling of transcriptome and proteome adaptation during development and heat stress response of tomato pollen
Keller, Mario; Consortium, SPOT-ITN; Simm, Stefan (2018)
BMC genomics 19 (1), 447.
DOI: 10.1186/s12864-018-4824-5
Open Access Peer Reviewed
BACKGROUND: Pollen development is central for plant reproduction and is assisted by changes of the transcriptome and proteome. At the same time, pollen development and viability is largely sensitive to stress, particularly to elevated temperatures. The transcriptomic and proteomic changes during pollen development and of different stages in response to elevated temperature was targeted to define the underlying molecular principles. RESULTS: The analysis of the transcriptome and proteome of Solanum lycopersicum pollen at tetrad, post-meiotic and mature stage before and after heat stress yielded a decline of the transcriptome but an increase of the proteome size throughout pollen development. Comparison of the transcriptome and proteome led to the discovery of two modes defined as direct and delayed translation. Here, genes of distinct functional processes are under the control of direct and delayed translation. The response of pollen to elevated temperature occurs rather at proteome, but not as drastic at the transcriptome level. Heat shock proteins, proteasome subunits, ribosomal proteins and eukaryotic initiation factors are most affected. On the example of heat shock proteins we demonstrate a decoupling of transcript and protein levels as well as a distinct regulation between the developmental stages. CONCLUSIONS: The transcriptome and proteome of developing pollen undergo drastic changes in composition and quantity. Changes at the proteome level are a result of two modes assigned as direct and delayed translation. The response of pollen to elevated temperature is mainly regulated at the proteome level, whereby proteins related to synthesis and degradation of proteins are most responsive and might play a central role in the heat stress response of pollen.
Zum Stand der Forschung zu „außergewöhnlichen Erfahrungen“ und ihren psychologischen Auswirkungen
Mayer, C. H.; Kohls, Niko (2018)
In G. Juckel, K. Hoffmann, & H. Walach (Eds.), Spiritualität in Psychiatrie & Psychotherapie (pp. 237 - 250). Lengerich: Pabst, 237-250.
Transnational Patients: Practical and Ethical Implications for Medical Practices and Health Promotions Policy
Zeldes, N.; Dilger, H.; FitzGerald, Kevin; Kohls, Niko; Moore, E.; Nöfer, Eberhard; Giordano, J. (2018)
Zeldes, N.; Dilger, H.; FitzGerald, Kevin; Kohls, Niko; Moore, E.; Nöfer, Eberhard...
World Medical & Health Policy 2018 / 10 (2), 198–207.
DOI: 10.1002/wmh3.263
Peer Reviewed
Social support and psychological distress in cancer: Stress as a mediator
Treaster, M. K.; Sirios , F. ; Offenbächer, M.; Toussaint, L.; Kohls, Niko; Nöfer, Eberhard; Hirsch, J. K. (2018)
Treaster, M. K.; Sirios , F. ; Offenbächer, M.; Toussaint, L.; Kohls, Niko...
Presentation at 33rd annual Appalachian Student Research Forum, ETSU, Johnson City, TN..
Peer Reviewed
Self-compassion and cancer: Perceived control, treatment adherence, and health status
Treaster, M. K.; Sirois, F. M.; Toussaint, L.; Offenbächer, M.; Kohls, Niko; Nöfer, Eberhard; Hirsch, J. K. (2018)
Treaster, M. K.; Sirois, F. M.; Toussaint, L.; Offenbächer, M.; Kohls, Niko...
Presentation at 64th annual meeting of the Southeastern Psychological Association, Charleston, SC..
Peer Reviewed
A Workplace Mindfulness Intervention May Be Associated With Improved Psychological Well-Being and Productivity. A Preliminary Field Study in a Company Setting
Kersemaekers, W.; Rupprecht, S.; Wittmann, M.; Tamdjidi, C.; Falke, P.; Donders, R.; Speckens, A.; Kohls, Niko (2018)
Kersemaekers, W.; Rupprecht, S.; Wittmann, M.; Tamdjidi, C.; Falke, P.; Donders, R....
A Preliminary Field Study in a Company Setting. Frontiers in Psychology, 9(195). doi:10.3389/fpsyg.2018.00195 18/9 (195).
DOI: 10.3389/fpsyg.2018.00195
Peer Reviewed
The association between different spiritual practices and the occurrence of Exceptional Human Experiences in a non-clinical sample
Carmona-Torres, J. A.; Kohls, Niko; Hood, R. W.; Silver, C. F.; Walach, H. (2018)
Journal for the Study of Spirituality 2018 / 8 (1), 49–64.
DOI: 10.1080/20440243.2018.1431035
Peer Reviewed
Mindfulness-Based Coping With University Life: A Randomized Wait-List Controlled Study. SAGE Open, 8(1), 1-7. doi:10.1177/2158244018758379
Lynch, S.; Gander, M.; Nahar, A.; Kohls, Niko; Walach, H. (2018)
Peer Reviewed
Monitoring of Soft Deposition Layers in Liquid-Filled Tubes with Guided Acoustic Waves Excited by Clamp-on Transducers
Tietze, Sabrina; Singer, F.; Lasota, Sandra; Ebert, Sandra; Landskron, Johannes; Schwuchow, Katrin; Drese, Klaus Stefan; Lindner, Gerhard (2018)
Tietze, Sabrina; Singer, F.; Lasota, Sandra; Ebert, Sandra; Landskron, Johannes...
Sensors 2018 18 (2), 526.
DOI: 10.3390/s18020526
Open Access Peer Reviewed
The monitoring of liquid-filled tubes with respect to the formation of soft deposition layers such as biofilms on the inner walls calls for non-invasive and long-term stable sensors, which can be attached to existing pipe structures. For this task a method is developed, which uses an ultrasonic clamp-on device. This method is based on the impact of such deposition layers on the propagation of circumferential guided waves on the pipe wall. Such waves are partly converted into longitudinal compressional waves in the liquid, which are back-converted to guided waves in a circular cross section of the pipe. Validating this approach, laboratory experiments with gelatin deposition layers on steel tubes exhibited a distinguishable sensitivity of both wave branches with respect to the thickness of such layers. This allows the monitoring of the layer growth.
Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors
Lampe, Sebastian; Kunze, Michael; Scholz, Anica; Brauß, Thilo; Winslow, Sofia; Simm, Stefan; Keller, Mario; Heidler, Juliana; Wittig, Ilka; Brüne, Bernhard; Schmid, Tobias (2018)
Lampe, Sebastian; Kunze, Michael; Scholz, Anica; Brauß, Thilo; Winslow, Sofia...
Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms 1861 (2), 147–157.
DOI: 10.1016/j.bbagrm.2018.01.010
Open Access Peer Reviewed
EINBLICKE IN UNSICHTBARE WELTEN - Überwachung der Biofilmbildung durch innovative Schallsensorik
Kufner, Maria; Drese, Klaus Stefan; Schwuchow, K. (2018)
Jahresmagazin Mess- und Sensortechnik 2017/2018, 70-74.
Klassisches oder digitales Stressmanagement im Setting Hochschule?
Nagel, Andreas; John, Dennis; Scheder, A.; Kohls, Niko (2018)
Prävention und Gesundheitsförderung 2018 / 53 (2), 83.
DOI: 10.1007/s11553-018-0670-1
Peer Reviewed
Gefühl und Vernunft als leibliches Erleben – Zur Relevanz von Subjektivität für anthropologische und ethische Bezüge im Kontext von Gesundheitsförderung
Röhrich, Christina; Krüger, Eckard; Kohls, Niko (2018)
Internationale Zeitschrift für Philosophie und Psychosomatik 2018 (1), 1–9.
Peer Reviewed
Stuck in the Past with Angry Memories has detrimental Health Effects in Patients suffering from Fibromyalgia
Toussaint, L.; Sirois, F. M.; Hirsch, J. K.; Kohls, Niko; Weber, Annemarie; Schelling, J.; Vajda, C.; Offenbächer, M. (2017)
Toussaint, L.; Sirois, F. M.; Hirsch, J. K.; Kohls, Niko; Weber, Annemarie...
Schmerz 2017 31 (Suppl 2):S59.
Peer Reviewed
An Altered Subjective Time Perspective is associated with Symptoms and Quality of Life in Patients suffering from Fibromyalgia
Offenbächer, M.; Sirois, F. M.; Toussaint, L.; Hirsch, J. K.; Weber, Annemarie; Kohls, Niko; Schelling, J.; Wittmann, M. (2017)
Offenbächer, M.; Sirois, F. M.; Toussaint, L.; Hirsch, J. K.; Weber, Annemarie...
Schmerz 2017 31 (Suppl 2):S59.
Peer Reviewed
Gratitude Mediates Quality of Life Differences Between Fibromyalgia Patients and Healthy Controls
Toussaint, L.; Sirois, F. M.; Hirsch, J. K.; Weber, Annemarie; Vajda, C.; Schelling, J.; Kohls, Niko; Offenbächer, M. (2017)
Toussaint, L.; Sirois, F. M.; Hirsch, J. K.; Weber, Annemarie; Vajda, C.; Schelling, J....
Schmerz 2017 31 (Suppl 2):S60.
Peer Reviewed
Fakultät Angewandte Naturwissenschaften und Gesundheit (FNG)
Hochschule Coburg
Friedrich-Streib-Str. 2
96450 Coburg
Jakob Hanke
Forschungsreferent
T +49 9561 317 360
jakob.hanke[at]hs-coburg.de