The perceived benefit and harm of mild radon hyperthermia, rehabilitation and medications from the point of view of a large cohort of patients with ankylosing spondylitis (AS) attending the Gastein Healing Gallery
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A.; Lunzer, R.; Herold, Manfred; Untner, J.; Kohls, Niko; Hölzl, B.; Gaisberger, M.; Toussaint, L. (2020)
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A....
Eingereicht Österreichischer Kongress für Rheumatologie 2020..
Peer Reviewed
The perceived benefit and harm of active exercise, physical therapy and modalities of a large cohort of patients with ankylosing spondylitis (AS) attending the Gastein Healing Gallery
Offenbacher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A.; Lunzer, R.; Untner, J.; Kohls, Niko; Hölzl, B.; Gaisberger, M.; Toussaint, L. (2020)
Offenbacher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A....
Eingereicht Österreichischer Kongress für Rheumatologie 2020.
Peer Reviewed
Effects of the Gastein Healing Gallery on physical functioning, activity and participation – results of qualitative interviews of 14 patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) or fibromyalgia syndrome (FMS)
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Toussaint, L.; Kohls, Niko; Sirios , F. ; Untner, J.; Hirsch, J. K. (2020)
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Toussaint, L.; Kohls, Niko...
J Miner Stoffwechs Muskuloskelet Erkrank: 27:141.
Peer Reviewed
The perceived benefit and harm of mild radon hyperthermia, rehabilitation and medications from the point of view of a large cohort of patients with ankylosing spondylitis (AS)
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A.; Lunzer, R.; Untner, J.; Kohls, Niko; Hölzl, B.; Gaisberger, M.; Toussaint, L. (2020)
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A....
attending the Gastein Healing Gallery. J Miner Stoffwechs Muskuloskelet Erkrank;27:145.
Peer Reviewed
The perceived benefit and harm of active exercise, physical therapy and modalities of a large cohort of patients with ankylosing spondylitis (AS) attending the Gastein Healing Gallery
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A.; Lunzer, R.; Untner, J.; Kohls, Niko; Hölzl, B.; Gaisberger, M.; Toussaint, L. (2020)
Offenbaecher, M.; Hirsch, J. K.; Sirios , F. ; van der Zee-Neuen, A.; Scharmga, A....
J Miner Stoffwechs Muskuloskelet Erkrank: 27:142.
Peer Reviewed
Effects of the Gastein Healing Gallery on medication use and physical and mental health – results of qualitative interviews of 14 patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) or fibromyalgia syndrome (FMS)
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Kohls, Niko; Toussaint, L.; Sirios , F. ; van der Zee-Neuen, A.; Untner, J.; Hirsch, J. K. (2020)
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Kohls, Niko; Toussaint, L....
Suppl2:S96.
Peer Reviewed
Positive Psychological Traits and Functional Impairment in Chronic Pain: Do Reduced Stress, Pain, and Fatigue Explain the Benefits?
Altier, H.; Offenbaecher, M.; Toussaint, L.; Kohls, Niko; Sirois, F.; van der Zee-Neuen, A.; Hirsch, J. K. (2020)
Altier, H.; Offenbaecher, M.; Toussaint, L.; Kohls, Niko; Sirois, F....
Posterpräsentation beim Deutschen Schmerzkongress 2020..
Peer Reviewed
Effects of the Gastein Healing Gallery on medication use and physical and mental health – results of qualitative interviews of 14 patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) or fibromyalgia syndrome (FMS)
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Kohls, Niko; Toussaint, L.; Sirios , F. ; van der Zee-Neuen, A.; Untner, J.; Hirsch, J. K. (2020)
Offenbaecher, M.; Zerhoch, Tamara; Nöfer, Eberhard; Kohls, Niko; Toussaint, L....
Posterpräsentation beim Deutschen Schmerzkongress 2020..
Peer Reviewed
Positive Psychological Traits and Functional Impairment in Chronic Pain: Do Reduced Stress, Pain, and Fatigue Explain the Benefits?
Altier, H.; Offenbaecher, M.; Toussaint, L.; Kohls, Niko; Sirios , F. ; van der Zee-Neuen, A.; Hirsch, J. K. (2020)
Altier, H.; Offenbaecher, M.; Toussaint, L.; Kohls, Niko; Sirios , F. ...
Schmerz;34 Suppl.2: S91.
Peer Reviewed
Of Nemesis and Narcissus: Lessons COVID may provide for enterprises – and ethics – of global health promotion and biosecurity
DiEuliis, D.; Kohls, Niko; Giordano, J. (2020)
In M. Woesler & H. M. Sass (Eds.), Medicine and Ethics in Times of Corona (pp. 323 - 327), 323-327.
Educational needs of patients with rheumatic and musculoskeletal diseases attending a large health facility in Austria
Hirsch, Jameson; Toussaint, L.; Offenbächer, M.; Kohls, Niko; Hanshans, Christian ; Vallejo, M.; Rivera, J.; Sirios , F. ; Untner, J.; Hölzl, B.; Gaisberger, M.; Ndosi, M. (2020)
Hirsch, Jameson; Toussaint, L.; Offenbächer, M.; Kohls, Niko; Hanshans, Christian ...
Musculoskeletal Care, n/a(n/a). 2020 / 18 (3), 391 - 396.
DOI: 10.1002/msc.1474
Peer Reviewed
The Existence and Localization of Nuclear snoRNAs in Arabidopsis thaliana Revisited
Streit, Deniz; Shanmugam, Thiruvenkadam; Garbelyanski, Asen; Simm, Stefan; Schleiff, Enrico (2020)
Streit, Deniz; Shanmugam, Thiruvenkadam; Garbelyanski, Asen; Simm, Stefan...
Plants (Basel, Switzerland) 9 (8), 1016.
DOI: 10.3390/plants9081016
Open Access Peer Reviewed
Ribosome biogenesis is one cell function-defining process. It depends on efficient transcription of rDNAs in the nucleolus as well as on the cytosolic synthesis of ribosomal proteins. For newly transcribed rRNA modification and ribosomal protein assembly, so-called small nucleolar RNAs (snoRNAs) and ribosome biogenesis factors (RBFs) are required. For both, an inventory was established for model systems like yeast and humans. For plants, many assignments are based on predictions. Here, RNA deep sequencing after nuclei enrichment was combined with single molecule species detection by northern blot and in vivo fluorescence in situ hybridization (FISH)-based localization studies. In addition, the occurrence and abundance of selected snoRNAs in different tissues were determined. These approaches confirm the presence of most of the database-deposited snoRNAs in cell cultures, but some of them are localized in the cytosol rather than in the nucleus. Further, for the explored snoRNA examples, differences in their abundance in different tissues were observed, suggesting a tissue-specific function of some snoRNAs. Thus, based on prediction and experimental confirmation, many plant snoRNAs can be proposed, while it cannot be excluded that some of the proposed snoRNAs perform alternative functions than are involved in rRNA modification.
miRNAs involved in transcriptome remodeling during pollen development and heat stress response in Solanum lycopersicum
Keller, Mario; Schleiff, Enrico; Simm, Stefan (2020)
Scientific Reports 10 (1), 10694.
DOI: 10.1038/s41598-020-67833-6
Open Access Peer Reviewed
Cellular transitions during development and stress response depend on coordinated transcriptomic and proteomic alterations. Pollen is particular because its development is a complex process that includes meiotic and mitotic divisions which causes a high heat sensitivity of these cells. Development and stress response are accompanied by a reprogramming of the transcriptome, e.g. by post-transcriptional regulation via miRNAs. We identified known and potentially novel miRNAs in the transcriptome of developing and heat-stressed pollen of Solanum lycopersicum (tomato). The prediction of target mRNAs yielded an equal number of predicted target-sites in CDS and 3’UTR regions of target mRNAs. The result enabled the postulation of a possible link between miRNAs and a fine-tuning of transcription factor abundance during pollen development. miRNAs seem to play a role in the pollen heat stress response as well. We identified several heat stress transcription factors and heat shock proteins as putative targets of miRNAs in response to heat stress, thereby placing these miRNAs as important elements of thermotolerance. Moreover, for members of the AP2, SBP and ARF family members we could predict a miRNA-mediated regulation during development via the miR172, mir156 and mir160-family strengthening the current concept of a cross-connection between development and stress response in plants.
Freiheitsberaubung aus Fürsorge?! – Die Anwendung freiheitsentziehender Maßnahmen in der Pflege
Berzlanovich, A.; Kirsch, S.; Herold-Majumdar, A.; Kohls, Niko (2020)
In T. Gaertner, S. Knoblich, T. Muck, & M. Rieger (Eds.), Die Pflegeversicherung: Handbuch zur Begutachtung, Qualitätsprüfung, Beratung und Fortbildung (Vierte überarbeitete Auflage ed., pp. 637-646)., 637-646.
Depression and Pain in Patients with Rheumatic and Musculoskeletal Disease: Are Positive Psychological Characteristics Protective?
Altier, H.; Offenbaecher, M.; van der Zee-Neuen, A.; Toussaint, L.; Kohls, Niko; Hanshans, Christian ; Sirios , F. ; Untner, J.; Hölzl, B.; Gaisberger, M.; Hirsch, J. K. (2020)
Altier, H.; Offenbaecher, M.; van der Zee-Neuen, A.; Toussaint, L.; Kohls, Niko...
J Miner Stoffwechs Muskuloskelet Erkrank 27:145.
Peer Reviewed
Transcriptional Basis for Differential Thermosensitivity of Seedlings of Various Tomato Genotypes
Hu, Yangjie; Fragkostefanakis, Sotirios; Schleiff, Enrico; Simm, Stefan (2020)
Genes 11 (6), 655.
DOI: 10.3390/genes11060655
Open Access Peer Reviewed
Transcriptional reprograming after the exposure of plants to elevated temperatures is a hallmark of stress response which is required for the manifestation of thermotolerance. Central transcription factors regulate the stress survival and recovery mechanisms and many of the core responses controlled by these factors are well described. In turn, pathways and specific genes contributing to variations in the thermotolerance capacity even among closely related plant genotypes are not well defined. A seedling-based assay was developed to directly compare the growth and transcriptome response to heat stress in four tomato genotypes with contrasting thermotolerance. The conserved and the genotype-specific alterations of mRNA abundance in response to heat stress were monitored after exposure to three different temperatures. The transcripts of the majority of genes behave similarly in all genotypes, including the majority of heat stress transcription factors and heat shock proteins, but also genes involved in photosynthesis and mitochondrial ATP production. In turn, genes involved in hormone and RNA-based regulation, such as auxin- and ethylene-related genes, or transcription factors like HsfA6b, show a differential regulation that associates with the thermotolerance pattern. Our results provide an inventory of genes likely involved in core and genotype-dependent heat stress response mechanisms with putative role in thermotolerance in tomato seedlings.
Effekte von Lebensstiländerungen bei arterieller Hypertonie in der Primärversorgung - ein systematisches Review
Sanftenberg, L.; Badermann, M.; Kohls, Niko; Weber, Annemarie; Schelling, J.; Sirios , F. ; Toussaint, L.; Hirsch, Jameson; Offenbächer, M. (2020)
Sanftenberg, L.; Badermann, M.; Kohls, Niko; Weber, Annemarie; Schelling, J....
Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen, 150-152, 12-19. , 12-19.
DOI: 10.1016/j.zefq.2020.03.004
Peer Reviewed
Self-compassion and health in cardiac disease: Psychopathology as a mediator
Byerley, S.M.; Hirsch, J. K.; Weber, Annemarie; Kleinecke, C.; Hall, B.; Offenbächer, M.; Toussaint, L.; Sirios , F. ; Vajda, C.; Schelling, J.; Kohls, Niko; Brachmann, J. (2020)
Byerley, S.M.; Hirsch, J. K.; Weber, Annemarie; Kleinecke, C.; Hall, B....
Presentation at 66th annual conference of the Southeastern Psychological Association 2020, New Orleans, LA..
Peer Reviewed
Self-compassion and health in cardiac disease: Psychopathology as a mediator
Byerley, S. M.; Hirsch, J. K.; Weber, Annemarie; Kleinecke, C.; Hall, B.; Offenbaecher, M.; Toussaint, L.; Sirois, F.; Vajda, C.; Schelling, J.; Kohls, Niko; Brachmann, J. (2020)
Byerley, S. M.; Hirsch, J. K.; Weber, Annemarie; Kleinecke, C.; Hall, B....
Presentation at 66th annual conference of the Southeastern Psychological Association 2020, New Orleans, LA..
Peer Reviewed
Obituary: Professor Peter Gründler (1940–2019)
Flechsig, Gerd-Uwe (2020)
Journal of Solid State Electrochemistry 24, 795–796.
DOI: 10.1007/s10008-020-04518-0
Open Access Peer Reviewed
Fakultät Angewandte Naturwissenschaften und Gesundheit (FNG)
Hochschule Coburg
Friedrich-Streib-Str. 2
96450 Coburg
Monika Schnabel
Forschungsreferentin, EU-Referentin
T +49 9561 317 8062
monika.schnabel[at]hs-coburg.de