ISO 26262 Conformant Verification Plan
Nörenberg , R.; Reißing, Ralf; Weber, J. (2010)
Informatik 2010, 8. Workshop Automotive Software Engineering, September 2010, Leipzig, , 515-520.
Peer Reviewed
Chloroplast import signals: the length requirement for translocation in vitro and in vivo
Bionda, Tihana; Tillmann, Bodo; Simm, Stefan; Beilstein, Kim; Ruprecht, Maike; Schleiff, Enrico (2010)
Bionda, Tihana; Tillmann, Bodo; Simm, Stefan; Beilstein, Kim; Ruprecht, Maike...
Journal of Molecular Biology 402 (3), 510–523.
DOI: 10.1016/j.jmb.2010.07.052
Open Access Peer Reviewed
Protein translocation of cytosolically synthesized proteins requires signals for both targeting of precursor proteins to the surface of the respective compartment and their transfer across its membrane. In contrast to signals for peroxisomal and endoplasmic reticulum translocation, the signals for mitochondrial and chloroplast transport are less well defined with respect to length and amino acid requirements. To study the properties of signals required for translocation into chloroplasts in vitro and in vivo, we used fusion proteins composed of transit peptides and the Ig-like module of the muscle protein titin as passenger. We observed that about 60 amino acids-longer than the transit peptide length of many experimentally confirmed chloroplast proteins-are required for efficient translocation. However, within native chloroplast precursor proteins with transit peptides shorter than 60 amino acids, extension appears to be present as they are efficiently imported into organelles. In addition, the interaction of an unfolded polypeptide stretch of 60 or more amino acids with receptors at the chloroplast surface results in the unidirectionality of protein translocation into chloroplasts even in the presence of a competing C-terminal peroxisomal targeting signal. These findings prove the existing ideas that initial targeting is defined by the N-terminal signal and that the C-terminal signal is sensed only subsequently.
Die Aktie: ein Derivat! Eine ökonomische Analyse der Besteuerung von Beteiligungserfolgen unter Einbeziehung der Steuersysteme in Deutschland und Kanada
Demmler, Uwe (2010)
2010.
The origins of the modern concept of “neuroscience´´ - Wilhelm Wundt between empiricism and idealism: implications for contemporary neuroethics.
Kohls, Niko; Benedikter, R. (2010)
In J. Giordano & B. Gordijn , (Eds.), Scientific and Philosophical Perspectives in Neuroethics (pp. 37 - 65). Cambridge: University Press., 37-65.
Open Access
Liberty-depriving Methods: A special form of violence against elderly people within the context of nursing
Berzlanovich, A.; Plischke , Herbert ; Sauer, S.; Holzer, N.; Kohls, Niko (2010)
International Network für the Prevention of Elder Abuse (INPEA), 2010. http://www.inpea.net/cgi-bin/FormMail. weaad events.pl.
Ambient Assistive Technologies (AAT): socio-technology as a powerful tool for facing the inevitable sociodemographic challenges?
Schülke, A.; Plischke , Herbert ; Kohls, Niko (2010)
Philosophy, Ethics, and Humanities in Medicine, 5 (1), 8..
Peer Reviewed
European Violence Prevention in Health Network and Colleagues. Liberty-depriving Methods: A special form of violence against elderly people within the context of nursing
Plischke , Herbert ; Kohls, Niko (2010)
Innovation - Implementation – Sustainability. Proceedings 2010. Fulda, 1.
Peer Reviewed
Are basic need satisfaction and mindfulness complementary in nature?
Lenartz, N.; Kohls, Niko; Walach, H. (2010)
Poster Presentation. 4th International SDT Conference, Gent University, Belgium.
Peer Reviewed
European Violence Prevention in Health Network and Colleagues. Liberty-depriving Methods: A special form of violence against elderly people within the context of nursing
Berzlanovich, A.; Sauer, S.; Holzer, N.; Plischke , Herbert ; Kohls, Niko (2010)
Innovation Implementation – Sustain-ability. Fulda, 06.-07.05.2010.
Peer Reviewed
Single-electron transistors based on self-assembled silicon-on-insulator quantum dots
Wolf, Conrad R.; Thonke, Klaus; Sauer, Rolf (2010)
Appl. Phys. Lett. 96 (14), 142108.
DOI: 10.1063/1.3383235
We present an approach to fabricate single-electron devices consisting of a silicon quantum dot (QD) between metallic leads. Silicon QDs are obtained by reactive ion etching into a silicon-on-insulator substrate partially protected by a self-assembled etch mask. Electrodes are fabricated and aligned to the QDs by an electromigration process whereby their native oxide serves as tunneling barrier. The devices show Coulomb blockade corresponding to a charging energy of 19.4 meV and can be switched from the nonconducting to a conducting state giving rise to Coulomb diamonds. The behavior is well reproduced by a numerical orthodox theory calculation.
Transport of Alzheimer disease amyloid-beta-binding D-amino acid peptides across an in vitro blood-brain barrier model
Liu, Hongmei ; Funke, Susanne A.; Willbold, Dieter (2010)
Rejuvenation Res. 13, , 210-213..
DOI: 10.1089/rej.2009.0926
Open Access Peer Reviewed
Stichtagserhebung „Freiheitsentziehende Maßnahmen“ zum „Annual World Elder Abuse Awareness Day“ am 15. Juni 2008
Randzio, O; Herold-Majumdar, A.; Berzlanovich, A.; Plischke , Herbert ; Kohls, Niko (2010)
Forum für Geriatrie Bad Hofgastein 2010. Geriatrie – Quo vadis? Bad Hofgastein, 08-11.03.2010.
Peer Reviewed
Umgang mit freiheitsentziehenden Maßnahmen in Altenpflegeeinrichtungen - Bayernweite Fragebogenaktion am 15. Juni 2008
Berzlanovich, A.; Randzio, O; Herold-Majumdar, A.; Plischke , Herbert ; Kohls, Niko (2010)
Tagungsband 2010. Forum für Geriatrie Bad Hofgastein 2010. Geriatrie – Quo vadis? Bad Hofgastein.
Peer Reviewed
Stichtagserhebung „Freiheitsentziehende Maßnahmen“ zum „Annual World Elder Abuse Awareness Day“ am 15. Juni 2008
Randzio, O; Herold-Majumdar, A.; Berzlanovich, A.; Plischke , Herbert ; Kohls, Niko (2010)
Tagungband 2010. Forum für Geriatrie Bad Hofgastein 2010. Geriatrie – Quo vadis? Bad Hofgastein..
Peer Reviewed
Assistive technologies: ethical, legal, philosophical and psychological issues’
Schülke, A.; Sauer, S.; Plischke , Herbert ; Kohls, Niko (2010)
3 AAL-Congress, Berlin.
Peer Reviewed
Competitively selected protein ligands pay their increase in specificity by a decrease in affinity
Hoffmann, Silke; Funke, Susanne A.; Wiesehan , Katja ; Moedder, Susanne; Glück , J. M. ; Feuerstein , Sophie; Gerdts , Matthias ; Mötter, Jessica ; Willbold, Dieter (2010)
Hoffmann, Silke; Funke, Susanne A.; Wiesehan , Katja ; Moedder, Susanne...
Mol. Biosyst. 6, , 126-133..
DOI: 10.1039/B910945E
Open Access Peer Reviewed
Oral Treatment with the D-Enantiomeric Peptide D3 Improves Pathology and Behavior of Alzheimer’s disease Transgenic
Funke, Susanne A.; van Groen, Thomas; Kadish, Inga; Bartnik , Dirk ; Nagel-Steger, Luitgard; Brener, Oleksandr; Sehl, Torsten ; Batra-Safferling , Renu ; Moriscot , Christine; Schoehn , Guy ; Horn, A. H. C.; Müller-Schiffmann, A.; Korth , C.; Sticht, H.; Willbold, Dieter (2010)
Funke, Susanne A.; van Groen, Thomas; Kadish, Inga; Bartnik , Dirk ...
ACS Chem. Neurosci. 2010, 1, 9, 639–648, 639–648.
DOI: 10.1021/cn100057j
Open Access Peer Reviewed
Single particle detection system for Aß: Adaptation of surface-FIDA to laser scanning microscopy.
Funke, Susanne A.; Wang, L.; Birkmann, Eva; Willbold, Dieter (2010)
Rejuvenation Res. 13, , 206-209..
Peer Reviewed
Differently selected D-enantiomeric peptides act on different Aß species.
Bartnik , Dirk ; Funke, Susanne A.; Andrei-Selmer, L-C; Bacher, M.; Dodel, R.; Willbold, Dieter (2010)
Bartnik , Dirk ; Funke, Susanne A.; Andrei-Selmer, L-C; Bacher, M.; Dodel, R....
Rejuvenation Res. 13, 202-205.
Peer Reviewed
Recht im Spannungsfeld zwischen sozialpädagogischer und juristischer Methodik. Ein Beitrag zur Entwicklung, Bedeutung und methodischen Charakteristik psychosozial ausgerichteter Rechtsverwirklichung in Wissenschaft und Praxis. Zugleich ein Plädoyer für eine aktuelle methodische Standortbestimmung (Teil 2)
Buchholz-Schuster, Eckardt (2010)
Zeitschrift für Kindschaftsrecht und Jugendhilfe 2010 (1), 17-21.