Ultrasonic Interferometric Procedure for Quantifying Prosthesis Loosening
Lützelberger, Jan (2024)
Invited Talk, 87th Annual Meeting of the DPG - Deutsche Physikalische Gesellschaft, Berlin, 2024.
Loosening of an artificial hip joint is a frequent complication in orthopedics and trauma surgery. Due to a lack of accuracy, conventional diagnostic methods such as projection radiography cannot reliably diagnose loosening in its early stages or detect whether it is associated with the formation of a biofilm in the bone-implant interface.
In this work, we developed an ultrasonic measurement procedure for quantifying the thickness of the layer between bone and prosthesis as a correlate to loosening. In principle, it also allows for the material characterization of the interface. An analytical model for the reflection of sound waves in a three-layer system was combined with a new data processing method to face the challenges of the specific medical application. By non-linear fitting the theoretical prediction of the model to the actual shape of the reflected sound waves in frequency domain, the thickness of the interlayer can be determined and predictions about its physical properties are possible. The presented approach was successfully applied to idealized test systems and a bone-implant system for thickness determination in the range of approx. 200 µm to 2 mm [1].
The talk will focus on the physical background and the key concepts of the procedure as well as on representative experiments, but also highlight its future potential in medical application.
[1] J. Lützelberger et al., Sensors 23, 5942 (2023)
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Kohls, Niko (2024)
Gefangen in der Positivitätsfalle: Wann das Immer-Glücklich-Sein gefährlich wird
Kohls, Niko (2024)
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Funke, Susanne A. (2024)
AD/PD Conference 2024, Lissabon.
Selbstfürsorge ist en vogue - aber zu viel davon kann uns schaden
Kohls, Niko (2024)
Focus Online: https://www.focus.de/experts/die-seele-ins-gleichgewicht-bringen-psychologe-mit-7-tipps-wird-selbstfuersorge-zur-routine_id_259726954.html.
Frequency-Resolved High-Frequency Broadband Measurement of Acoustic Longitudinal Waves by Laser-Based Excitation and Detection
Brand, Felix; Drese, Klaus Stefan (2024)
Sensors 24 (5), 1630.
DOI: 10.3390/s24051630
Open Access Peer Reviewed
Optoacoustics is a metrology widely used for material characterisation. In this study, a measurement setup for the selective determination of the frequency-resolved phase velocities and attenuations of longitudinal waves over a wide frequency range (3-55 MHz) is presented. The ultrasonic waves in this setup were excited by a pulsed laser within an absorption layer in the thermoelastic regime and directed through a layer of water onto a sample. The acoustic waves were detected using a self-built adaptive interferometer with a photorefractive crystal. The instrument transmits compression waves only, is low-contact, non-destructive, and has a sample-independent excitation. The limitations of the approach were studied both by simulation and experiments to determine how the frequency range and precision can be improved. It was shown that measurements are possible for all investigated materials (silicon, silicone, aluminium, and water) and that the relative error for the phase velocity is less than 0.2%.
Beratung von pflegenden Angehörigen: Welche Anlaufstellen gibt es?
Esslinger, Adelheid Susanne (2024)
MMW Münchner Medizinihsce Wochenzeitschrift (3), 42-44.
Peer Reviewed
Tree species-specific wood traits control diazotrophic community composition in deadwood
Hossen, Shakhawat; Groß , C.; Stapf, D.; Borken , W.; Noll, Matthias (2024)
International Biodeterioration & Biodegradation 187, 105723 .
DOI: 10.1016/j.ibiod.2023.105723
Peer Reviewed
Mirror-image phage display for the selection of D-amino acid peptide ligands as potential therapeutics
Funke, Susanne A.; Malhis, Marwa (2024)
Current Protocolls 2024 (4), e957.
Open Access Peer Reviewed
Neues Verfahren zeigt Lockerung von Hüftgelenken im Mikrometerbereich
Reckter, Bettina (2024)
VDI nachrichten, 2024..
Künstliche Intelligenz: Trends, Gefahren und Chancen
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Groß , C.; Hossen, Shakhawat; Dittrich, S.; Knorr, K.-H.; Borken , W.; Noll, Matthias (2024)
Groß , C.; Hossen, Shakhawat; Dittrich, S.; Knorr, K.-H.; Borken , W....
Environmental Microbiology 26, e16555.
DOI: 10.1111/1462-2920.16555
Open Access Peer Reviewed
Vorstellung des Forschungsprojekts AI4Coping
Meißner, Karin; Grubert, Jens (2024)
Interview im TV Oberfranken, Sendung 4you: Das neue Hochschulmagazin.
Open Access
Quelle: TV Oberfranken
Poultry litter biochar soil amendment affects microbial community structures, promotes phosphorus cycling and growth of barley (Hordeum vulgare).
Deinert, L.; Hossen, Shakhawat; Ikoyi, I.; Kwapinksi, W.; Noll, Matthias; Schmalenberger, Achim (2024)
Deinert, L.; Hossen, Shakhawat; Ikoyi, I.; Kwapinksi, W.; Noll, Matthias...
European Journal of Soil Biology 120, 103591.
DOI: 10.1016/j.ejsobi.2023.103591
Peer Reviewed
Active soil microbial composition and proliferation are directly affected by the presence of biocides from building materials
Kalkhof, Stefan; Reiß, Fabienne; Kiefer, Nadine; Purahong, Witoon; Borken , W.; Noll, Matthias (2024)
Kalkhof, Stefan; Reiß, Fabienne; Kiefer, Nadine; Purahong, Witoon; Borken , W....
Science of the Total Environment 912, 168689.
DOI: 10.1016/j.scitotenv.2023.168689
Peer Reviewed
Mapping expectancy-based appetitive placebo effects onto the brain in women
Khalid, Iraj ; Rodrigues, Belina ; Dreyfus, Hippolyte ; Frileux, Solène ; Meißner, Karin; Fossati, Philippe ; Hare, Todd Anthony ; Schmidt, Liane (2024)
Khalid, Iraj ; Rodrigues, Belina ; Dreyfus, Hippolyte ; Frileux, Solène ...
Nature Communications 15, 248 | 1-16.
DOI: 10.1038/s41467-023-44569-1
Open Access Peer Reviewed
Eluates from facades at the beginning of their service time affect aquatic and sediment organisms
Kalkhof, Stefan; Kiefer, Nadine; Nichterlein, Moritz; Reiß, Fabienne; Runge, M.; Biermann, U.; Wieland, Thomas; Noll, Matthias (2024)
Kalkhof, Stefan; Kiefer, Nadine; Nichterlein, Moritz; Reiß, Fabienne; Runge, M....
Science of the Total Environment. 906, 167531.
DOI: 10.1016/j.scitotenv.2023.167531
Peer Reviewed
Low dose ribosomal DNA P-loop mutation affects development and enforces autophagy in Arabidopsis
Shanmugam, Thiruvenkadam; Chaturvedi, Palak; Streit, Deniz; Ghatak, Arindam; Bergelt, Thorsten; Simm, Stefan; Weckwerth, Wolfram; Schleiff, Enrico (2024)
Shanmugam, Thiruvenkadam; Chaturvedi, Palak; Streit, Deniz; Ghatak, Arindam...
RNA biology 21 (1), 1–15.
DOI: 10.1080/15476286.2023.2298532
Open Access Peer Reviewed
Arabidopsis contains hundreds of ribosomal DNA copies organized within the nucleolar organizing regions (NORs) in chromosomes 2 and 4. There are four major types of variants of rDNA, VAR1-4, based on the polymorphisms of 3’ external transcribed sequences. The variants are known to be differentially expressed during plant development. We created a mutant by the CRISPR-Cas9-mediated excision of ~ 25 nt from predominantly NOR4 ribosomal DNA copies, obtaining mosaic mutational events on ~ 5% of all rDNA copies. The excised region consists of P-loop and Helix-82 segments of 25S rRNA. The mutation led to allelic, dosage-dependent defects marked by lateral root inhibition, reduced size, and pointy leaves, all previously observed for defective ribosomal function. The mutation in NOR4 led to dosage compensation from the NOR2 copies by elevated expression of VAR1 in mutants and further associated single-nucleotide variants, thus, resulting in altered rRNA sub-population. Furthermore, the mutants exhibited rRNA maturation defects specifically in the minor pathway typified by 32S pre-rRNA accumulation. Density-gradient fractionation and subsequent RT-PCR of rRNA analyses revealed that mutated copies were not incorporated into the translating ribosomes. The mutants in addition displayed an elevated autophagic flux as shown by the autophagic marker GFP-ATG8e, likely related to ribophagy.
Leadership as a Mental Shield: How Leaders of Specialised Police Units Can Promote Inner Resilience and Mental Stability.
Jäger, Tamara; Giordano, J.; Kohls, Niko (2023)
, 401-425.
Peer Reviewed
Guided Acoustic Waves in Polymer Rods with Varying Immersion Depth in Liquid
Lutter, Klaus; Backer, Alexander; Drese, Klaus Stefan (2023)
Sensors 2023 (23), 9892.
DOI: 10.3390/s23249892
Open Access Peer Reviewed
Fakultät Angewandte Naturwissenschaften und Gesundheit (FNG)
Hochschule Coburg
Friedrich-Streib-Str. 2
96450 Coburg
Monika Schnabel
Forschungsreferentin, EU-Referentin
T +49 9561 317 8062
monika.schnabel[at]hs-coburg.de