Self-reported general health and depression among persons with cancer: can gratitude make a difference?
Goodin, S.; Treaster, M. K.; Rabon, J.; Sirois, F. M.; Offenbächer, M.; Kohls, Niko; Toussaint, L.; Hirsch, J. K. (2017)
Goodin, S.; Treaster, M. K.; Rabon, J.; Sirois, F. M.; Offenbächer, M.; Kohls, Niko...
Presentation at the 32nd annual Appalachian Student Research Forum, East Tennessee State University, Johnson City, TN, USA 2017.
Peer Reviewed
Social support and health related quality of life among chronically ill: serial indirect effects of depressive symptoms and treatment adherence
Montgomery, M.; Brooks, B.; Kohls, Niko; Offenbächer, M.; Toussaint, L.; Sirois, F. M.; Hirsch, J. K. (2017)
Montgomery, M.; Brooks, B.; Kohls, Niko; Offenbächer, M.; Toussaint, L.; Sirois, F. M....
Presentation at the 32nd annual Appalachian Student Research Forum, East Tennessee State University, Johnson City, TN, USA 2017.
Peer Reviewed
Psychophysiology of duration estimation in experienced mindfulness meditators and matched controls
Otten, S.; Schötz, E.; Wittmann, M.; Kohls, Niko; Schmidt, S.; Meißner, Karin (2017)
In N. Farb, C. Kerr, W.E. Mehling & O. Pollatos, O. (Eds.), Interoception, Contemplative Practice, and Health. Lausanne: Frontiers Media.
DOI: https://doi.org.10.3389/978-2-88945-094-7
Control beliefs and suicide risk in cancer patients: Conditional indirect effects of future health perception, gratitude, and optimism
Hirsch, J. K.; Kohls, Niko; Offenbächer, M.; Pugh, K.; Sirois, F. M.; Toussaint, L.; Treaster, M. K. (2017)
Hirsch, J. K.; Kohls, Niko; Offenbächer, M.; Pugh, K.; Sirois, F. M.; Toussaint, L....
Presentation at the 64th annual conference of Tennessee Psychological Association, Nashville, TN. Awarded 2nd Place in Graduate Oral Presentation Competition..
Peer Reviewed
Future orientation and fibromyalgia impact: Indirect effects of treatment adherence
Treaster, M. K.; Pugh, K.; Sirois, F. M.; Kohls, Niko; Nöfer, Eberhard; Hirsch, J. K. (2017)
Treaster, M. K.; Pugh, K.; Sirois, F. M.; Kohls, Niko; Nöfer, Eberhard...
Presentation at the 64th annual conference of Tennessee Psychological Association, Nashville, TN. Awarded 1st Place in Graduate Oral Presentation Competition..
Peer Reviewed
Struggling With Adversities of Life: The Role of Forgiveness in Patients Suffering from Fibromyalgia
Offenbaecher, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M. A.; Rivera, J.; Bauerdorf, F.; Schelling, J.; Vincent, A.; Hirsch, J. K.; Sirois, F. M.; Webb, J. R.; Toussaint, L. (2017)
Offenbaecher, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M. A.; Rivera, J....
The Clinical journal of pain 2017 / 33 (6), 528–534.
DOI: 10.1097/AJP.0000000000000432
Peer Reviewed
OBJECTIVES
Alternative splicing in tomato pollen in response to heat stress
Keller, Mario; Hu, Yangjie; Mesihovic, Anida; Fragkostefanakis, Sotirios; Schleiff, Enrico; Simm, Stefan (2017)
Keller, Mario; Hu, Yangjie; Mesihovic, Anida; Fragkostefanakis, Sotirios...
DNA research: an international journal for rapid publication of reports on genes and genomes 24 (2), 205–217.
DOI: 10.1093/dnares/dsw051
Open Access Peer Reviewed
Alternative splicing (AS) is a key control mechanism influencing signal response cascades in different developmental stages and under stress conditions. In this study, we examined heat stress (HS)-induced AS in the heat sensitive pollen tissue of two tomato cultivars. To obtain the entire spectrum of HS-related AS, samples taken directly after HS and after recovery were combined and analysed by RNA-seq. For nearly 9,200 genes per cultivar, we observed at least one AS event under HS. In comparison to control, for one cultivar we observed 76% more genes with intron retention (IR) or exon skipping (ES) under HS. Furthermore, 2,343 genes had at least one transcript with IR or ES accumulated under HS in both cultivars. These genes are involved in biological processes like protein folding, gene expression and heat response. Transcriptome assembly of these genes revealed that most of the alternative spliced transcripts possess truncated coding sequences resulting in partial or total loss of functional domains. Moreover, 141 HS specific and 22 HS repressed transcripts were identified. Further on, we propose AS as layer of stress response regulating constitutively expressed genes under HS by isoform abundance.
Selection and characterization of tau protein binding peptides as basis for future therapies for Alzheimer`s
Dammers, C.; Yolcu , D.; Kukuk, Laura; Willbold, Dieter; Pickhardt, Marcus ; Mandelkow, E.; Horn, A. H. C.; Sticht, H.; Malhis, M.; Will, Nadja ; Schuster, Judith ; Funke, Susanne A. (2016)
Dammers, C.; Yolcu , D.; Kukuk, Laura; Willbold, Dieter; Pickhardt, Marcus ...
AD/PD 2019.
DOI: 10.1371/journal.pone.0167432
Peer Reviewed
Functional limitations in children and adolescents suffering from chronic pain: validation and psychometric properties of the German Functional Disability Inventory (FDI-G)
Offenbächer, M.; Kohls, Niko; Walker, L.; Hermann, C.; Hügle, B.; Jäger,, N.; Richter,, M.; Haas, J.-P (2016)
Offenbächer, M.; Kohls, Niko; Walker, L.; Hermann, C.; Hügle, B.; Jäger,, N....
Rheumatology International, 1-10. doi:10.1007/s00296-016-3504-5.
DOI: 10.1007/s00296-016-3504-5
Peer Reviewed
Ansätze zur Steigerung der körperlichen Aktivität von Patienten in Allgemeinarztpraxen – ein narrativer Review
van Dyck, M.; Weber, Annemarie; Schelling, J.; Kohls, Niko; Poggenburg, S.; Offenbächer, M. (2016)
van Dyck, M.; Weber, Annemarie; Schelling, J.; Kohls, Niko; Poggenburg, S....
50. Kongress für Allgemein- und Familienmedizin, Frankfurt; 29.9.2016.
Peer Reviewed
Eine Forschungsidee zum Stellenwert und zur Bedeutung der Gesundheitsförderung aus Sicht von MedizinstudentInnen im Studium und im Fach Allgemeinmedizin
Weber, Annemarie; Schelling, J.; Kohls, Niko; van Dyck, M.; Nöfer, Eberhard; Offenbächer, M. (2016)
Weber, Annemarie; Schelling, J.; Kohls, Niko; van Dyck, M.; Nöfer, Eberhard...
50. Kongress für Allgemein- und Familienmedizin, Frankfurt; 29.9.2016.
Peer Reviewed
50 years of amino acid hydrophobicity scales: revisiting the capacity for peptide classification
Simm, Stefan; Einloft, Jens; Mirus, Oliver; Schleiff, Enrico (2016)
Biological Research 49 (1), 31.
DOI: 10.1186/s40659-016-0092-5
Open Access Peer Reviewed
BACKGROUND: Physicochemical properties are frequently analyzed to characterize protein-sequences of known and unknown function. Especially the hydrophobicity of amino acids is often used for structural prediction or for the detection of membrane associated or embedded β-sheets and α-helices. For this purpose many scales classifying amino acids according to their physicochemical properties have been defined over the past decades. In parallel, several hydrophobicity parameters have been defined for calculation of peptide properties. We analyzed the performance of separating sequence pools using 98 hydrophobicity scales and five different hydrophobicity parameters, namely the overall hydrophobicity, the hydrophobic moment for detection of the α-helical and β-sheet membrane segments, the alternating hydrophobicity and the exact ß-strand score. RESULTS: Most of the scales are capable of discriminating between transmembrane α-helices and transmembrane β-sheets, but assignment of peptides to pools of soluble peptides of different secondary structures is not achieved at the same quality. The separation capacity as measure of the discrimination between different structural elements is best by using the five different hydrophobicity parameters, but addition of the alternating hydrophobicity does not provide a large benefit. An in silico evolutionary approach shows that scales have limitation in separation capacity with a maximal threshold of 0.6 in general. We observed that scales derived from the evolutionary approach performed best in separating the different peptide pools when values for arginine and tyrosine were largely distinct from the value of glutamate. Finally, the separation of secondary structure pools via hydrophobicity can be supported by specific detectable patterns of four amino acids. CONCLUSION: It could be assumed that the quality of separation capacity of a certain scale depends on the spacing of the hydrophobicity value of certain amino acids. Irrespective of the wealth of hydrophobicity scales a scale separating all different kinds of secondary structures or between soluble and transmembrane peptides does not exist reflecting that properties other than hydrophobicity affect secondary structure formation as well. Nevertheless, application of hydrophobicity scales allows distinguishing between peptides with transmembrane α-helices and β-sheets. Furthermore, the overall separation capacity score of 0.6 using different hydrophobicity parameters could be assisted by pattern search on the protein sequence level for specific peptides with a length of four amino acids.
Life is sparse: The Role of Gratitude in Patients Suffering from Fibromyalgia. 05/2016
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
Conference: 8th European Conference on Positive Psychology, Angers, Frankreich,28.6.-1.7.2016; DOI: 10.13140/RG.2.1.4511.5768.
DOI: https://doi.org.10.13140/RG.2.1.4511.5768
Peer Reviewed
Achtsamkeit in der Schule (AISCHU): Ein Konzept zur Integration von Achtsamkeit in den Schulalltag
Weber, Annemarie; Kretschmer, M.; Uhlemayr, M.; Kaltwasser, V.; Kohls, Niko (2016)
Empirische Pädagogik, 30(2), 5-20..
Peer Reviewed
Acoustic boosting of battery charging
Tietze, Sabrina; Lindner, Gerhard (2016)
Proceedings Actuator16, 451 - 454.
The kinetics of the charge transport across the solid-liquid interface between the electrode and the electrolyte is controlled by a diffusion boundary layer, which is responsible for the time needed for charging the battery. Therefore a removal of this boundary layer by acoustic streaming induced by surface acoustic waves propagating on the electrodes was considered to be promising approach for a reduction of the charging time. Previous electropolishing experiments have shown that Scholte waves were particularly effective in that respect. This concept has been transferred to a model electrode system representing the core of a lead acid battery, where significant reductions of the charging time and corresponding increases of the charging currents resulting from surface acoustic wave sonication have been observed.
Trying to be perfect in an imperfect world: The role of perfectionism in adjustment to fibromyalgia. 05/2016
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
8th European Conference on Positive Psychology, Angers, Frankreich,28.6.-1.7.2016, DOI: 10.13140/RG.2.1.1365.8482.
DOI: https://doi.org.10.13140/RG.2.1.1365.8482
Peer Reviewed
Struggling with Adversities of Life: The Role of Forgiveness in Patients Suffering from Fibromyalgia. 05/2016
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Sirois, F.; Poggenburg, S.; Toussaint, L. (2016)
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J....
8th European Conference on Positive Psychology, Angers, Frankreich,28.6.-1.7.2016, DOI: 10.13140/RG.2.1.2414.4246.
DOI: https://doi.org.10.13140/RG.2.1.2414.4246
Peer Reviewed
.Life is sparse: The Role of Gratitude in Patients Suffering from Fibromyalgia. 05/2016, Conference: 1
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
Deutschen Kongress für Forschung in der Positiven Psychologie in Trier, 19.-21. Mai 2016.
Peer Reviewed
Trying to be perfect in an imperfect world: The role of perfectionism in adjustment to fibromyalgia
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
Conference: 1. Deutschen Kongress für Forschung in der Positiven Psychologie in Trier, 19.-21. Mai 2016.
Peer Reviewed
Struggling with Adversities of Life: The Role of Forgiveness in Patients Suffering from Fibromyalgia
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Sirois, F.; Poggenburg, S.; Toussaint, L. (2016)
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J....
1. Deutschen Kongress für Forschung in der Positiven Psychologie in Trier, 19.-21. Mai 2016.
Peer Reviewed
Fakultät Angewandte Naturwissenschaften und Gesundheit (FNG)
Hochschule Coburg
Friedrich-Streib-Str. 2
96450 Coburg
Monika Schnabel
Forschungsreferentin, EU-Referentin
T +49 9561 317 8062
monika.schnabel[at]hs-coburg.de