Brand, Felix; Singer, Ferdinand; Drese, Klaus Stefan (2019)
LUS4Metals. Linz, .
Rowe, C.; Sirios , F. ; Toussaint, L.; Kohls, Niko; Nöfer, Eberhard; Offenbacher, M.; Hirsch, J. K. (2019)
Rowe, C.; Sirios , F. ; Toussaint, L.; Kohls, Niko; Nöfer, Eberhard; Offenbacher, M....
Psychology, Health & Medicine, 24(8), 962-977. Retrieved from https://doi.org/10.1080/13548506.2019.1576913. doi:10.1080/13548506.2019.1576913, 962-977.
DOI: 10.1080/13548506.2019.1576913
Walach, H.; Kohls, Niko (2019)
In G. Lucchetti, M. F. Prieto Peres, & R. F. Damiano (Eds.), Spirituality, Religiousness and Health: From Research to Clinical Practice (pp. 33-48)., 33-48.
Röhrich, Christina; Karl, V.; Pfeifer, G.; John, Dennis; Kohls, Niko (2019)
Das Gesundheitswesen, 81(08/09), 712-712. doi:10.1055/s-0039-1694507.
DOI: doi:10.1055/s-0039-1694507
Zagel, Christian (2019)
Kronach, Usability User Experience Roadshow.
Larcher, Marco; Troi, Alexandra; Demattio, Martina (2019)
Proceedings of Building Simulation 2019, 2.-4.9.2019 in Rome, Italy, 2634–2641.
DOI: 10.26868/25222708.2019.210411
Markert, Michael; Stocker, Gerfried; Schöpf, Christine; Leopoldseder, Hannes (2019)
Out of the Box: the midlife crisis of the digital revolution 2019.
El-Shershaby, Asmaa; Ullrich, Sarah; Simm, Stefan; Scharf, Klaus-Dieter; Schleiff, Enrico; Fragkostefanakis, Sotirios (2019)
El-Shershaby, Asmaa; Ullrich, Sarah; Simm, Stefan; Scharf, Klaus-Dieter...
Gene 714, 143985.
DOI: 10.1016/j.gene.2019.143985
In all eukaryotes, the response to heat stress (HS) is dependent on the activity of HS transcription factors (Hsfs). Plants contain a large number of Hsfs, however, only members of the HsfA1 subfamily are considered as master regulators of stress response and thermotolerance. In Solanum lycopersicum, among the four HsfA1 members, only HsfA1a has been proposed to possess a master regulator function. We performed a comparative analysis of HsfA1a, HsfA1b, HsfA1c and HsfA1e at different levels of regulation and function. HsfA1a is constitutively expressed under control and stress conditions, while the other members are induced in specific tissues and stages of HS response. Despite that all members are localized in the nucleus when expressed in protoplasts, only HsfA1a shows a wide range of basal activity on several HS-induced genes. In contrast, HsfA1b, HsfA1c, and HsfA1e show only high activity for specific subsets of genes. Domain swapping mutants between HsfA1a and HsfA1c revealed that the variation in that transcriptional transactivation activity is due to differences in the DNA binding domain (DBD). Specifically, we identified a conserved arginine (R107) residue in the turn of β3 and β4 sheet in the C-terminus of the DBD of HsfA1a that is highly conserved in plant HsfA1 proteins, but is replaced by leucine and cysteine in tomato HsfA1c and HsfA1e, respectively. Although not directly involved in DNA interaction, R107 contributes to DNA binding and consequently the activity of HsfA1a. Thus, we demonstrate that this variation in DBD in part explains the functional diversification of tomato HsfA1 members.
Schaub, Michael; Kriegel, Martin; Brandt, Stefan (2019)
International Journal of Heat and Mass Transfer 144, 118665.
DOI: 10.1016/j.ijheatmasstransfer.2019.118665
Kohls, Niko; Esch, Tobias; Gerber, L.; Adrian, L.; Wittmann, M. (2019)
Behavioral Sciences, 9(8), 87. Retrieved from https://www.mdpi.com/2076-328X/9/8/87 .
Bottino-Leone, Dario; Larcher, Marco; Herrera-Avellanosa, Daniel; Haas, Franziska; Troi, Alexandra (2019)
Bottino-Leone, Dario; Larcher, Marco; Herrera-Avellanosa, Daniel; Haas, Franziska...
Energy 181, 521–531.
DOI: 10.1016/j.energy.2019.05.139
Kovacevic, Jelena; Palm, Denise; Jooss, Domink; Bublak, Daniela; Simm, Stefan; Schleiff, Enrico (2019)
Kovacevic, Jelena; Palm, Denise; Jooss, Domink; Bublak, Daniela; Simm, Stefan...
Plant Cell Reports 38 (8), 937–949.
DOI: 10.1007/s00299-019-02416-y
Different genes coding for one ribosome biogenesis factor are differentially expressed and are likely under the control of distinct transcription factors, which contributes to the regulatory space for ribosome maturation. Maturation of ribosomes including rRNA processing and modification, rRNA folding and ribosome protein association requires the function of many ribosome biogenesis factors (RBFs). Recent studies document plant-specific variations of the generally conserved process of ribosome biogenesis. For instance, distinct rRNA maturation pathways and intermediates have been identified, the existence of plant specific RBFs has been proposed and several RBFs are encoded by multiple genes. The latter in combination with the discussed ribosome heterogeneity points to a possible function of the different proteins representing one RBF in diversification of ribosomal compositions. Such factor-based regulation would require a differential regulation of their expression, may be even controlled by different transcription factors. We analyzed the expression profiles of genes coding for putative RBFs and transcription factors. Most of the genes coding for RBFs are expressed in a comparable manner, while different genes coding for a single RBF are often differentially expressed. Based on a selected set of genes we document a function of the transcription factors AtMYC1, AtMYC2, AtbHLH105 and AtMYB26 on the regulation of different RBFs. Moreover, on the example of the RBFs LSG1 and BRX1, both encoded by two genes, we give a first hint on a differential transcription factor dependence of expression. Consistent with this observation, the phenotypic analysis of RBF mutants suggests a relation between LSG1-1 and BRX1-1 expression and the transcription factor MYC1. In summary, we propose that the multiple genes coding for one RBF are required to enlarge the regulatory space for ribosome biogenesis.
Röhrich, Christina; Kohls, Niko (2019)
Zeitschrift Herzblick – Das Merlin-AHF Projekt, Herausgeber Herzkind e. V. Sonderausgabe 3/2019.
Hirsch, J. K.; Sirios , F. ; Visser, P.; Brooks, B.; Kohls, Niko; Offenbacher, M.; Toussaint, L. (2019)
Hirsch, J. K.; Sirios , F. ; Visser, P.; Brooks, B.; Kohls, Niko; Offenbacher, M....
Perceived stigma and health-related quality of life in the working uninsured: Does thwarted belongingness play a role? Stigma and Health..
Toussaint, L.; Kohls, Niko; Hanshans, C.; Vallejo, M.; Rivera, J.; Sirois, F.; Hirsch, J. K.; Untner, J.; Hölzl, B.; Gaisberger, M.; Offenbächer, M. (2019)
Toussaint, L.; Kohls, Niko; Hanshans, C.; Vallejo, M.; Rivera, J.; Sirois, F....
Annals of the Rheumatic Diseases, 78(Suppl 2), 1046-1046. Retrieved from https://ard.bmj.com/content/annrheumdis/78/Suppl_2/1046.1.full.pdf. doi:10.1136/annrheumdis-2019-eular.5361 .
Offenbächer, M.; Kohls, Niko; Hanshans, Christian ; Vallejo, M.; Rivera, J.; Sirios , F. ; Hirsch, J. K.; Untner, J.; Hölzl, B.; Gaisberger, M.; Toussaint, L. (2019)
Offenbächer, M.; Kohls, Niko; Hanshans, Christian ; Vallejo, M.; Rivera, J....
Annals of the Rheumatic Diseases, 78(Suppl 2), 1046-1046. Retrieved from https://ard.bmj.com/content/annrheumdis/78/Suppl_2/1046.2.full.pdf. doi:10.1136/annrheumdis-2019-eular.4912.
Berzlanovich, A.; Kohls, Niko (2019)
In H. Walach & M. Loef (Eds.), Demenz – Prävention und Therapie (pp. 439 - 448). Essen: KVC., 439-448.
Offenbaecher, M.; Toussaint, L.; Kohls, Niko; Hanshans, Christian ; Vallejo, M.; Rivera, J.; Sirios , F. ; Hirsch, J. K.; Untner, J.; Hölzl, B.; Gaisberger, M.; Ndosi, M. (2019)
Offenbaecher, M.; Toussaint, L.; Kohls, Niko; Hanshans, Christian ; Vallejo, M....
Annals of the Rheumatic Diseases, 78(Suppl 2), 1442-1442. Retrieved from https://ard.bmj.com/content/annrheumdis/78/Suppl_2/1442.1.full.pdf. doi:10.1136/annrheumdis-2019-eular.5416.
Nagel, Andreas; John, Dennis; Kohls, Niko (2019)
Moment by Moment..
Röhrich, Christina; Kohls, Niko (2019)
Journal für angeborene Herzfehler, Band 7 7.
Hochschule Coburg
Friedrich-Streib-Str. 2
96450 Coburg