Mechanisms of osmoregulation and biomarker identification in human skin cells and plasma

Summary

Due to demographic changes, the proportion of individuals over the age of 65 in the german population is increasing. This trend favors the occurrence of various age-related diseases. One such issue is dehydration. Dehydration can be caused by multiple factors in old age, including physical changes (lower fluid reserves and reduced total body water), and insufficient fluid intake due to reduced thirst and medications. The skin’s involvement in dehydration is suggested by various factors such as reduced skin turgor and impaired wound healing. However, diagnosing dehydration in older individuals can be challenging due to the normal aging process, which can obscure diagnostic signs such as abnormal skin turgor.