Peptides for diagnoses and therapy of Alzheimer’s disease. Invited review, Current Pharmaceutical Design Journal, special issue "Peptides in Diagnosis and Therapy”

Funke, Susanne A.; Willbold, Dieter (2012)

Curr. Pharm. Design 18, S. 755-767.

A Survey of Peptides with Effective Therapeutic Potential in Alzheimer’s Disease Rodent Models or in Human Clinical Studies

Sun, Na; Funke, Susanne A.; Willbold, Dieter (2012)

Mini-Reviews in Medicinal Chemistry 12, 5, S. 388-398.
DOI: 10.2174/138955712800493942

Staining of Amyloid Beta (Abeta) Using (Immuno) Histochemical Techniques and Abeta42 Specific Peptides.

van Groen, Thomas; Kadish, Inga; Funke, Susanne A.; Willbold, Dieter (2011)

Neuroimaging for Clinicians - Combining Research and Practice. Edited by: Julio F. P. Peres..

Detection of Soluble Amyloid-β Oligomers and Insoluble High-Molecular-Weight Particles in CSF: Development of Methods with Potential for Diagnosis and Therapy Monitoring of Alzheimer's Disease

Funke, Susanne A. (2011)

Int J Alzheimers Dis .
DOI: 10.4061/2011/151645

Combining independent drug classes into superior, synergistically acting hybrid molecules

Müller-Schiffmann, A.; März-Berberich , Julia; Andreyeva , Aksana ; Rönicke , Raik ; Bartnik , Dirk ; Brener, Oleksandr; Kutzsche, Janine; Horn, A. H. C.; Hellmerth , Marco ; Polkowska , Jolenta ; Gottmann, Kurt; Reymann, Klaus G.; Funke, Susanne A.; Nagel-Steger, Luitgard; Moriscot , Christine; Schoehn , Guy ; Sticht, H.; Willbold, Dieter; Schrader, Thomas ; Korth , C. (2010)

Müller-Schiffmann, A.; März-Berberich , Julia; Andreyeva , Aksana ; Rönicke , Raik ...

Angew Chem Int Ed Engl 49.
DOI: 10.1002/anie.201004437

Transport of Alzheimer disease amyloid-beta-binding D-amino acid peptides across an in vitro blood-brain barrier model

Liu, Hongmei ; Funke, Susanne A.; Willbold, Dieter (2010)

Rejuvenation Res. 13, , S. 210-213..
DOI: 10.1089/rej.2009.0926

Competitively selected protein ligands pay their increase in specificity by a decrease in affinity

Hoffmann, Silke; Funke, Susanne A.; Wiesehan , Katja ; Moedder, Susanne; Glück , J. M. ; Feuerstein , Sophie; Gerdts , Matthias ; Mötter, Jessica ; Willbold, Dieter (2010)

Hoffmann, Silke; Funke, Susanne A.; Wiesehan , Katja ; Moedder, Susanne...

Mol. Biosyst. 6, , S. 126-133..
DOI: 10.1039/B910945E

Oral Treatment with the D-Enantiomeric Peptide D3 Improves Pathology and Behavior of Alzheimer’s disease Transgenic

Funke, Susanne A.; van Groen, Thomas; Kadish, Inga; Bartnik , Dirk ; Nagel-Steger, Luitgard; Brener, Oleksandr; Sehl, Torsten ; Batra-Safferling , Renu ; Moriscot , Christine; Schoehn , Guy ; Horn, A. H. C.; Müller-Schiffmann, A.; Korth , C.; Sticht, H.; Willbold, Dieter (2010)

Funke, Susanne A.; van Groen, Thomas; Kadish, Inga; Bartnik , Dirk ...

ACS Chem. Neurosci. 2010, 1, 9, 639–648, S. 639–648.
DOI: 10.1021/cn100057j

Single particle detection system for Aß: Adaptation of surface-FIDA to laser scanning microscopy.

Funke, Susanne A.; Wang, L.; Birkmann, Eva; Willbold, Dieter (2010)

Rejuvenation Res. 13, , S. 206-209..

Differently selected D-enantiomeric peptides act on different Aß species.

Bartnik , Dirk ; Funke, Susanne A.; Andrei-Selmer, L-C; Bacher, M.; Dodel, R.; Willbold, Dieter (2010)

Bartnik , Dirk ; Funke, Susanne A.; Andrei-Selmer, L-C; Bacher, M.; Dodel, R....

Rejuvenation Res. 13, S. 202-205.

Pyroglutamate formation influences solubility and amyloidogenicity of amyloid peptides

Schlenzig, Dagmar; Manhart, Susanne; Cinar, Yeliz ; Kleinschmidt , Martin ; Hauser, Gerd ; Willbold, Dieter; Funke, Susanne A.; Schilling , Stephan ; Demuth, Hans-Ulrich (2009)

Schlenzig, Dagmar; Manhart, Susanne; Cinar, Yeliz ; Kleinschmidt , Martin ...

Biochemistry 2009, 48, 29, , S. 7072–7078.
DOI: 10.1021/bi900818a

Detection of Amyloid-β Aggregates in Body Fluids: A Suitable Method for Early Diagnosis of Alzheimer's Disease?

Funke, Susanne A.; Birkmann, Eva; Willbold, Dieter (2009)

Current Alzheimer Research 6, 3, S. 285-289.
DOI: 10.2174/156720509788486536

Transient reduction of spontaneous neuronal network activity by sublethal amyloid beta (1-42) peptide concentrations

Görtz, Philipp; Opatz, Jessica; Siebler, Mario ; Funke, Susanne A.; Willbold, Dieter; Lange-Asschenfeldt , Chtistian (2009)

Görtz, Philipp; Opatz, Jessica; Siebler, Mario ; Funke, Susanne A.; Willbold, Dieter...

Journal of Neural Transmission volume 116, S. 351–355.
DOI: 10.1007/s00702-009-0188-y

In vitro and in vivo Staining Characteristics of Small, Fluorescent, Aβ42-Binding D-Enantiomeric Peptides in Transgenic AD Mouse Models

van Groen, Thomas; Kadish, Inga; Wiesehan , Katja ; Funke, Susanne A.; Willbold, Dieter (2009)

van Groen, Thomas; Kadish, Inga; Wiesehan , Katja ; Funke, Susanne A....

ChemMedChem Volume 4, Issue 2 4, 2, S. 276-282.
DOI: 10.1002/cmdc.200800289

Mirror image phage display - a method to generate D-peptide ligands for use in diagnostic or therapeutical applications?

Funke, Susanne A.; Willbold, Dieter (2009)

Molecular BioSystems 5, S. 783 - 786.
DOI: 10.1039/b904138a

Reduction of Alzheimer’s Disease Amyloid Plaque Load in Transgenic Mice by D3, a D-Enantiomeric Peptide Identified by Mirror Image Phage Display

van Groen, Thomas; Wiesehan , Katja ; Funke, Susanne A.; Kadish, Inga; Nagel-Steger, Luitgard; Willbold, Dieter (2008)

van Groen, Thomas; Wiesehan , Katja ; Funke, Susanne A.; Kadish, Inga...

ChemMedChem Volume 3, Issue 12 3, 12, S. 1848-1852.
DOI: 10.1002/cmdc.200800273

An ultra sensitive assay for early diagnosis of Alzheimer's disease

Funke, Susanne A.; Birkmann, Eva; Henke, Franziska; Görtz, Philipp; Lange-Asschenfeldt , Chtistian ; Riesner, Detlev; Willbold, Dieter (2008)

Funke, Susanne A.; Birkmann, Eva; Henke, Franziska; Görtz, Philipp...

Rejuvenation Research 2008 (11), S. 315-318.

A highly sensitive diagnostic assay for aggregate-related diseases, including prion diseases and Alzheimer's disease

Birkmann, Eva; Henke, Franziska; Funke, Susanne A.; Bannach , Oliver; Riesner, Detlev; Willbold, Dieter (2008)

Birkmann, Eva; Henke, Franziska; Funke, Susanne A.; Bannach , Oliver; Riesner, Detlev...

Rejuvenation Research 11, 2, S. 359-363..
DOI: 10.1089/rej.2008.0697

Evolution of Enantioselective Bacillus subtilis Lipase

Eggert, Thorsten ; Funke, Susanne A.; Andexer , JN; Reetz , Manfred T. ; Jaeger, Karl-Erich (2008)

Eggert, Thorsten ; Funke, Susanne A.; Andexer , JN; Reetz , Manfred T. ...

book chapter in: Protein Engineering Handbook, 1. Auflage 2008.

Single particle detection of Aβ aggregates associated with Alzheimer’s disease

Funke, Susanne A.; Birkmann, Eva; Henke, Franziska; Görtz, Philipp; Lange-Asschenfeldt , Chtistian ; Riesner, Detlev; Willbold, Dieter (2007)

Funke, Susanne A.; Birkmann, Eva; Henke, Franziska; Görtz, Philipp...

Biochemical and Biophysical Research Communications 364, 4, S. 902-907.
DOI: 10.1016/j.bbrc.2007.10.085