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Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity

Rudolph, Stephan; Klein, Antonia Nicole ; Tusche, Markus; Schlosser, Christine ; Elfgen , Anne; Brener, Oleksandr; Teunisssen , Charlotte; Gremer, Lothar; Funke, Susanne A.; Kutzsche, Janine; Willbold, Dieter (2016)

Rudolph, Stephan; Klein, Antonia Nicole ; Tusche, Markus; Schlosser, Christine ...

PLOS ONE 11, 2.
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QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

Brener, Oleksandr; Dunkelmann, Tina; Gremer, Lothar; van Groen, Thomas; Mirecka, Ewa A.; Kadish, Inga; Willuweit, Antje; Kutzsche, Janine; Jürgens, Dagmar; Rudolph, Stephan; Tusche, Markus; Bongen, Patrick; Pietruszka, Jörg; Oesterhelt, Filipp; Langen, Karl-Josef; Demuth, Hans-Ulrich; Janssen, Arnold; Hoyer, Wolfgang; Funke, Susanne A.; Nagel-Steger, Luitgard; Willbold, Dieter (2015)

Brener, Oleksandr; Dunkelmann, Tina; Gremer, Lothar; van Groen, Thomas; Mirecka, Ewa A....

Scientific Reports 5, 13222.
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Structure characterization of unexpected covalent O-sulfonation and ion-pairing on an extremely hydrophilic peptide with CE-MS and FT-ICR-MS

Pattky, Martin ; Nicolardi , Simone ; Santiago-Schübel , Beatrix ; Sydes , Daniel ; van der Burgt , Yuri E. M.; Klein, Antonia Nicole ; Jiang , Nan; Mohrlüder, Jeannine ; Hänel , Karen ; Kutzsche, Janine; Funke, Susanne A.; Willbold, Dieter; Willbold , S.; Huhn, C. (2015)

Pattky, Martin ; Nicolardi , Simone ; Santiago-Schübel , Beatrix ; Sydes , Daniel ...

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Tailoring the Antibody Response to Aggregated Aß Using Novel Alzheimer-Vaccines

Mandler, Markus; Santic, Radmila ; Gruber , Petra; Cinar, Yeliz ; Pichler, Dagmar ; Funke, Susanne A.; Willbold, Dieter; Schneeberger , Achim ; Schmidt , Walter; Mattner , Frank (2015)

Mandler, Markus; Santic, Radmila ; Gruber , Petra; Cinar, Yeliz ; Pichler, Dagmar ...

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QIAD assay for quantitating a compound`s efficacy in elimination of toxic Aß oligomers

Brener, Oleksandr; Dunkelmann, Tina; Gremer, Lothar; van Groen, Thomas; Mirecka, Ewa A.; Kadish, Inga; Willuweit, Antje; Kutzsche, Janine; Jürgens, Dagmar; Rudolph, Stephan; Tusche, Markus; Bongen, Patrick; Pietruszka, Jörg; Oesterhelt, Filipp; Langen, Karl-Josef; Demuth, Hans-Ulrich; Janssen, Arnold; Hoyer, Wolfgang; Funke, Susanne A.; Nagel-Steger, Luitgard; Willbold, Dieter (2015)

Brener, Oleksandr; Dunkelmann, Tina; Gremer, Lothar; van Groen, Thomas; Mirecka, Ewa A....

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Detection and Quantitation of Amyloid-β Aggregates in Body Fluids may be Suitable for Early Diagnosis of Alzheimer’s Disease

Funke, Susanne A.; Birkmann, Eva; Willbold, Dieter (2014)

Advances in Alzheimer's Research 2.
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The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity

Widera , Marek ; Klein, Antonia Nicole ; Cinar, Yeliz ; Funke, Susanne A.; Willbold, Dieter; Schaal , Heiner (2014)

Widera , Marek ; Klein, Antonia Nicole ; Cinar, Yeliz ; Funke, Susanne A....

AIDS Research and Therapy 11, 1.
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Amyloid aggregation inhibitory mechanism of arginine-rich D-peptides

Olubiyi , O. O. ; Frenzel , Oliver ; Bartnik , Dirk ; Glück , J. M. ; Brener, Oleksandr; Nagel-Steger, Luitgard; Funke, Susanne A.; Willbold, Dieter; Strodel , B. (2014)

Olubiyi , O. O. ; Frenzel , Oliver ; Bartnik , Dirk ; Glück , J. M. ; Brener, Oleksandr...

National Library of Medicine National Center for Biotechnology Information, 1448-57.
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Treatment with D3 Removes Amyloid Deposits, Reduces Inflammation, and Improves Cognition in Old AβPP/PS1 Double Transgenic Mice

van Groen, Thomas; Kadish, Inga; Funke, Susanne A.; Bartnik , Dirk ; Willbold, Dieter (2013)

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J Alzheimers Dis. 2013; 34(3): 609–620. , 34, S. 609-620.
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Characterization of a single-chain variable fragment recognizing a linear epitope of Aß: A biotechnical tool for studies on Alzheimer's disease?

Dornieden, Silke; Müller-Schiffmann, A.; Sticht, H.; Cinar, Yeliz ; Wördehoff, M.; Korth , C.; Funke, Susanne A.; Willbold, Dieter (2013)

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The amyloid-β oligomer count in cerebrospinal fluid is a biomarker for Alzheimer's disease

Wang-Dietrich , Lei ; Funke, Susanne A.; Kühlbach , Katja ; Wang , Kun; Besmehn, Astrid ; Willbold , S.; Cinar, Yeliz ; Bannach , Oliver; Birkmann, Eva; Willbold, Dieter (2013)

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Structural analysis of the pyroglutamate-modified isoform of the Alzheimer's disease-related amyloid-β using NMR spectroscopy

Sun, Na; Hartmann, Rudolf ; Lecher, Justin ; Stoldt , Matthias ; Funke, Susanne A.; Gremer, Lothar; Ludwig , Hans-Henning ; Demuth, Hans-Ulrich; Kleinschmidt , Martin ; Willbold, Dieter (2012)

Sun, Na; Hartmann, Rudolf ; Lecher, Justin ; Stoldt , Matthias ; Funke, Susanne A....

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Mirror image phage display--generating stable therapeutically and diagnostically active peptides with biotechnological means

Sun, Na; Funke, Susanne A.; Willbold, Dieter (2012)

J Biotechnol 161, 2.
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A survey of peptides with effective therapeutic potential in Alzheimer's disease rodent models or in human clinical studies

Sun, Na; Funke, Susanne A.; Willbold, Dieter (2012)

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A synthetic amino acid substitution of Tyr10 in Aβ peptide sequence yields a dominant negative variant in amyloidogenesis

Mazargui , Honoree; Lévêque , Christian ; Bartnik , Dirk ; Fantini , Jacques ; Melone, Mariarosa A.B. ; Funke, Susanne A.; Willbold, Dieter; Perrone , Lorena (2012)

Mazargui , Honoree; Lévêque , Christian ; Bartnik , Dirk ; Fantini , Jacques ...

Aing Cell 11, 3.
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Identification and Characterization of an Aβ Oligomer Precipitating Peptide That May Be Useful to Explore Gene Therapeutic Approaches to Alzheimer Disease

Funke, Susanne A.; Liu, Hongmei ; Sehl, Torsten ; Bartnik , Dirk ; Brener, Oleksandr; Nagel-Steger, Luitgard; Wiesehan , Katja ; Willbold, Dieter (2012)

Funke, Susanne A.; Liu, Hongmei ; Sehl, Torsten ; Bartnik , Dirk ; Brener, Oleksandr...

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Detection of α-synuclein aggregates by fluorescence microscopy

Hübinger, S. ; Bannach , Oliver; Funke, Susanne A.; Funke, Susanne A.; Willbold, Dieter; Birkmann, Eva (2012)

Hübinger, S. ; Bannach , Oliver; Funke, Susanne A.; Funke, Susanne A....

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Development of a small D-enantiomeric Alzheimer's amyloid-β binding peptide ligand for future in vivo imaging applications

Funke, Susanne A.; Bartnik , Dirk ; Glück , J. M. ; Piorkowska , Kasia ; Wiesehan , Katja ; Weber, Urs; Gulyas , Balazs ; Halldin , Christer; Pfeifer, Andrea ; Sprenger, Christian ; Muhs , Andreas ; Willbold, Dieter (2012)

Funke, Susanne A.; Bartnik , Dirk ; Glück , J. M. ; Piorkowska , Kasia ...

PLOS One , 7.
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Treatment with Aβ42 binding D-amino acid peptides reduce amyloid deposition and inflammation in APP/PS1 double transgenic mice

van Groen, Thomas; Kadish, Inga; Funke, Susanne A.; Bartnik , Dirk ; Willbold, Dieter (2012)

van Groen, Thomas; Kadish, Inga; Funke, Susanne A.; Bartnik , Dirk ...

Advances in Protein Chemistry and Structural Biology 88, S. 133-152.
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