Dimensionierung von Luftleitungen bei SFP-Wert- bzw. Druckverlustvorgaben. Methodik auf Basis des gleichwertigen Durchmessers.
Schaub, Michael; Kriegel, Martin (2016)
HLH 67 (7), 33-37.
Open Access
50 years of amino acid hydrophobicity scales: revisiting the capacity for peptide classification
Simm, Stefan; Einloft, Jens; Mirus, Oliver; Schleiff, Enrico (2016)
Biological Research 49 (1), 31.
DOI: 10.1186/s40659-016-0092-5
Open Access Peer Reviewed
BACKGROUND: Physicochemical properties are frequently analyzed to characterize protein-sequences of known and unknown function. Especially the hydrophobicity of amino acids is often used for structural prediction or for the detection of membrane associated or embedded β-sheets and α-helices. For this purpose many scales classifying amino acids according to their physicochemical properties have been defined over the past decades. In parallel, several hydrophobicity parameters have been defined for calculation of peptide properties. We analyzed the performance of separating sequence pools using 98 hydrophobicity scales and five different hydrophobicity parameters, namely the overall hydrophobicity, the hydrophobic moment for detection of the α-helical and β-sheet membrane segments, the alternating hydrophobicity and the exact ß-strand score. RESULTS: Most of the scales are capable of discriminating between transmembrane α-helices and transmembrane β-sheets, but assignment of peptides to pools of soluble peptides of different secondary structures is not achieved at the same quality. The separation capacity as measure of the discrimination between different structural elements is best by using the five different hydrophobicity parameters, but addition of the alternating hydrophobicity does not provide a large benefit. An in silico evolutionary approach shows that scales have limitation in separation capacity with a maximal threshold of 0.6 in general. We observed that scales derived from the evolutionary approach performed best in separating the different peptide pools when values for arginine and tyrosine were largely distinct from the value of glutamate. Finally, the separation of secondary structure pools via hydrophobicity can be supported by specific detectable patterns of four amino acids. CONCLUSION: It could be assumed that the quality of separation capacity of a certain scale depends on the spacing of the hydrophobicity value of certain amino acids. Irrespective of the wealth of hydrophobicity scales a scale separating all different kinds of secondary structures or between soluble and transmembrane peptides does not exist reflecting that properties other than hydrophobicity affect secondary structure formation as well. Nevertheless, application of hydrophobicity scales allows distinguishing between peptides with transmembrane α-helices and β-sheets. Furthermore, the overall separation capacity score of 0.6 using different hydrophobicity parameters could be assisted by pattern search on the protein sequence level for specific peptides with a length of four amino acids.
Life is sparse: The Role of Gratitude in Patients Suffering from Fibromyalgia. 05/2016
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
Conference: 8th European Conference on Positive Psychology, Angers, Frankreich,28.6.-1.7.2016; DOI: 10.13140/RG.2.1.4511.5768.
DOI: https://doi.org.10.13140/RG.2.1.4511.5768
Peer Reviewed
Achtsamkeit in der Schule (AISCHU): Ein Konzept zur Integration von Achtsamkeit in den Schulalltag
Weber, Annemarie; Kretschmer, M.; Uhlemayr, M.; Kaltwasser, V.; Kohls, Niko (2016)
Empirische Pädagogik, 30(2), 5-20..
Peer Reviewed
Acoustic boosting of battery charging
Tietze, Sabrina; Lindner, Gerhard (2016)
Proceedings Actuator16, 451 - 454.
The kinetics of the charge transport across the solid-liquid interface between the electrode and the electrolyte is controlled by a diffusion boundary layer, which is responsible for the time needed for charging the battery. Therefore a removal of this boundary layer by acoustic streaming induced by surface acoustic waves propagating on the electrodes was considered to be promising approach for a reduction of the charging time. Previous electropolishing experiments have shown that Scholte waves were particularly effective in that respect. This concept has been transferred to a model electrode system representing the core of a lead acid battery, where significant reductions of the charging time and corresponding increases of the charging currents resulting from surface acoustic wave sonication have been observed.
Trying to be perfect in an imperfect world: The role of perfectionism in adjustment to fibromyalgia. 05/2016
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
8th European Conference on Positive Psychology, Angers, Frankreich,28.6.-1.7.2016, DOI: 10.13140/RG.2.1.1365.8482.
DOI: https://doi.org.10.13140/RG.2.1.1365.8482
Peer Reviewed
Struggling with Adversities of Life: The Role of Forgiveness in Patients Suffering from Fibromyalgia. 05/2016
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Sirois, F.; Poggenburg, S.; Toussaint, L. (2016)
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J....
8th European Conference on Positive Psychology, Angers, Frankreich,28.6.-1.7.2016, DOI: 10.13140/RG.2.1.2414.4246.
DOI: https://doi.org.10.13140/RG.2.1.2414.4246
Peer Reviewed
.Life is sparse: The Role of Gratitude in Patients Suffering from Fibromyalgia. 05/2016, Conference: 1
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Toussaint, L.; Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
Deutschen Kongress für Forschung in der Positiven Psychologie in Trier, 19.-21. Mai 2016.
Peer Reviewed
Trying to be perfect in an imperfect world: The role of perfectionism in adjustment to fibromyalgia
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Poggenburg, S.; Sirois, F. (2016)
Offenbächer, M.; Toussaint, L.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M....
Conference: 1. Deutschen Kongress für Forschung in der Positiven Psychologie in Trier, 19.-21. Mai 2016.
Peer Reviewed
Struggling with Adversities of Life: The Role of Forgiveness in Patients Suffering from Fibromyalgia
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J.; Weber, Annemarie; Schelling, J.; Vincent, A.; Hirsch, J. K.; Sirois, F.; Poggenburg, S.; Toussaint, L. (2016)
Offenbächer, M.; Dezutter, J.; Kohls, Niko; Sigl, C.; Vallejo, M.; Rivera, J....
1. Deutschen Kongress für Forschung in der Positiven Psychologie in Trier, 19.-21. Mai 2016.
Peer Reviewed
Methods for the Specific Detection and Quantitation of Amyloid-β Oligomers in Cerebrospinal Fluid
Schuster, Judith ; Funke, Susanne A. (2016)
J Alzheimers Dis 53, 53-67.
DOI: 10.3233/JAD-151029
Peer Reviewed
Individual Differences in Mindfulness – Special Issue
Jonason, P.; Kohls, Niko; Nadler, R.; Yoshinori, S. (2016)
Personality and Individual Differences, Volume 93, Pages 1-142 93, 1-142.
Open Access
Time perception, mindfulness and attentional capacities in transcendental meditators and matched controls
Schötz, E.; Otten, S.; Wittmann, M.; Schmidt, S.; Kohls, Niko; Meißner, Karin (2016)
Personality and Individual Differences, 93, 16-21., 16-21.
Peer Reviewed
Gleichwertiger Durchmesser: druckverlust-orientierte Dimensionierung von Luftleitungen
Schaub, Michael; Kriegel, Martin (2016)
TGA-Kongress, 14.-15.04.2016 in Berlin.
DOI: 10.13140/RG.2.2.10099.81440
Open Access
Soziale Arbeit und Menschenrechte
Lohrenscheit , Claudia (2016)
Schnuppervorlesungen im Rahmen der Schnuppertage an der Hochschule Coburg .
On the viability of neurotechnology and mind–body methods in pediatric mental health: Perspectives on integrating new tools to complement old techniques
Armon, E.; Kohls, Niko; Giordano, J. (2016)
European Journal of Integrative Medicine, 8(2), 137-140., 137-140.
Peer Reviewed
Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination
Klein, Antonia Nicole ; Ziehm , Tamar ; Tusche, Markus; Buitenhuis , Johan ; Bartnik , Dirk ; Boeddrich , Annett ; Wiglenda , Thomas; Wanker , Erich ; Funke, Susanne A.; Brener, Oleksandr; Gremer, Lothar; Kutzsche, Janine; Willbold, Dieter (2016)
Klein, Antonia Nicole ; Ziehm , Tamar ; Tusche, Markus; Buitenhuis , Johan ...
Plos One .
DOI: 10.1371/journal.pone.0153035
Open Access Peer Reviewed
HsfA2 Controls the Activity of Developmentally and Stress-Regulated Heat Stress Protection Mechanisms in Tomato Male Reproductive Tissues
Fragkostefanakis, Sotirios; Mesihovic, Anida; Simm, Stefan; Paupière, Marine; Hu, Yangjie; Paul, Puneet; Mishra, Shravan; Tschiersch, Bettina; Theres, Klaus; Bovy, Arnaud; Schleiff, Enrico; Scharf, Klaus-Dieter (2016)
Fragkostefanakis, Sotirios; Mesihovic, Anida; Simm, Stefan; Paupière, Marine...
Plant Physiology 170 (4), 2461–2477.
DOI: 10.1104/pp.15.01913
Open Access Peer Reviewed
Male reproductive tissues are more sensitive to heat stress (HS) compared to vegetative tissues, but the basis of this phenomenon is poorly understood. Heat stress transcription factors (Hsfs) regulate the transcriptional changes required for protection from HS In tomato (Solanum lycopersicum), HsfA2 acts as coactivator of HsfA1a and is one of the major Hsfs accumulating in response to elevated temperatures. The contribution of HsfA2 in heat stress response (HSR) and thermotolerance was investigated in different tissues of transgenic tomato plants with suppressed HsfA2 levels (A2AS). Global transcriptome analysis and immunodetection of two major Hsps in vegetative and reproductive tissues showed that HsfA2 regulates subsets of HS-induced genes in a tissue-specific manner. Accumulation of HsfA2 by a moderate HS treatment enhances the capacity of seedlings to cope with a subsequent severe HS, suggesting an important role for HsfA2 in regulating acquired thermotolerance. In pollen, HsfA2 is an important coactivator of HsfA1a during HSR HsfA2 suppression reduces the viability and germination rate of pollen that received the stress during the stages of meiosis and microspore formation but had no effect on more advanced stages. In general, pollen meiocytes and microspores are characterized by increased susceptibility to HS due to their lower capacity to induce a strong HSR This sensitivity is partially mitigated by the developmentally regulated expression of HsfA2 and several HS-responsive genes mediated by HsfA1a under nonstress conditions. Thereby, HsfA2 is an important factor for the priming process that sustains pollen thermotolerance during microsporogenesis.
Quantitation of Amyloid-β oligomers in human body fluids for Alzheimer’s disease early diagnosis or therapy monitoring
Funke, Susanne A.; Willbold, Dieter (2016)
Alzheimer's diagnosis, 1-24.
DOI: 10.3233/JAD-151029
Spiritualität und außergewöhnliche Erfahrungen im Kontext der akademischen Psychologie
Kohls, Niko (2016)
In L. Hofmann & P. Heise (Eds.), Spiritualität und spirituelle Krisen: Handbuch zu Theorie, Forschung und Praxis (pp. 3-12). Stuttgart: Schattauer., 3-12.