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Quantitation of Amyloid-β oligomers in human body fluids for Alzheimer’s disease early diagnosis or therapy monitoring

Funke, Susanne A.; Willbold, Dieter (2016)

Alzheimer's diagnosis, 1-24.
DOI: 10.3233/JAD-151029


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Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity

Rudolph, Stephan; Klein, Antonia Nicole ; Tusche, Markus; Schlosser, Christine ...

PLOS ONE 11, 2.
DOI: 10.1371/journal.pone.0147470


Open Access Peer Reviewed
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Structure characterization of unexpected covalent O-sulfonation and ion-pairing on an extremely hydrophilic peptide with CE-MS and FT-ICR-MS

Pattky, Martin ; Nicolardi , Simone ; Santiago-Schübel , Beatrix ; Sydes , Daniel ...

Analytical and Bioanalytical Chemistry volume 407 407 (22), 6637-55.
DOI: 10.1007/s00216-015-8826-8


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Tailoring the Antibody Response to Aggregated Aß Using Novel Alzheimer-Vaccines

Mandler, Markus; Santic, Radmila ; Gruber , Petra; Cinar, Yeliz ; Pichler, Dagmar ...

PLOS ONE.
DOI: 10.1371/journal.pone.0115237


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Detection and Quantitation of Amyloid-β Aggregates in Body Fluids may be Suitable for Early Diagnosis of Alzheimer’s Disease

Funke, Susanne A.; Birkmann, Eva; Willbold, Dieter (2014)

Advances in Alzheimer's Research 2.
DOI: 10.2174/9781608058525114020013


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The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity

Widera , Marek ; Klein, Antonia Nicole ; Cinar, Yeliz ; Funke, Susanne A....

AIDS Research and Therapy 11, 1.
DOI: 10.1186/1742-6405-11-1


Open Access Peer Reviewed
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Amyloid aggregation inhibitory mechanism of arginine-rich D-peptides

Olubiyi , O. O. ; Frenzel , Oliver ; Bartnik , Dirk ; Glück , J. M. ; Brener, Oleksandr...

National Library of Medicine National Center for Biotechnology Information, 1448-57.
DOI: 10.2174/0929867321666131129122247


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Treatment with D3 Removes Amyloid Deposits, Reduces Inflammation, and Improves Cognition in Old AβPP/PS1 Double Transgenic Mice

van Groen, Thomas; Kadish, Inga; Funke, Susanne A.; Bartnik , Dirk ...

J Alzheimers Dis. 2013; 34(3): 609–620. , 34 | 609-620.
DOI: 10.3233/JAD-121792


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Characterization of a single-chain variable fragment recognizing a linear epitope of Aß: A biotechnical tool for studies on Alzheimer's disease?

Dornieden, Silke; Müller-Schiffmann, A.; Sticht, H.; Cinar, Yeliz ; Wördehoff, M....

Lawrence, Kan. PLoS 2013 , 8 | e59820.
DOI: 10.1371/journal.pone.0059820


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The amyloid-β oligomer count in cerebrospinal fluid is a biomarker for Alzheimer's disease

Wang-Dietrich , Lei ; Funke, Susanne A.; Kühlbach , Katja ; Wang , Kun...

National Library of Medicine National Center for Biotechnology Information, 34.
DOI: 10.3233/JAD-122047.


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Structural analysis of the pyroglutamate-modified isoform of the Alzheimer's disease-related amyloid-β using NMR spectroscopy

Sun, Na; Hartmann, Rudolf ; Lecher, Justin ; Stoldt , Matthias ; Funke, Susanne A....

J Pept Sci 2012 Nov;18(11):691-5 2012, 18.
DOI: 10.1002/psc.2456


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Mirror image phage display--generating stable therapeutically and diagnostically active peptides with biotechnological means

Sun, Na; Funke, Susanne A.; Willbold, Dieter (2012)

J Biotechnol 161, 2.
DOI: 10.1016/j.jbiotec.2012.05.019


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A synthetic amino acid substitution of Tyr10 in Aβ peptide sequence yields a dominant negative variant in amyloidogenesis

Mazargui , Honoree; Lévêque , Christian ; Bartnik , Dirk ; Fantini , Jacques ...

Aing Cell 11, 3.
DOI: 10.1111/j.1474-9726.2012.00814.x


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Identification and Characterization of an Aβ Oligomer Precipitating Peptide That May Be Useful to Explore Gene Therapeutic Approaches to Alzheimer Disease

Funke, Susanne A.; Liu, Hongmei ; Sehl, Torsten ; Bartnik , Dirk ; Brener, Oleksandr...

Rejuvenation Research Vol. 15, No. 2 15, 2 | 144-147..
DOI: 10.1089/rej.2011.1262


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Detection of α-synuclein aggregates by fluorescence microscopy

Hübinger, S. ; Bannach , Oliver; Funke, Susanne A.; Funke, Susanne A....

Rejuvenation Res. 15, 15, 2 | 213- 216..
DOI: 10.1089/rej.2011.1288


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Development of a small D-enantiomeric Alzheimer's amyloid-β binding peptide ligand for future in vivo imaging applications

Funke, Susanne A.; Bartnik , Dirk ; Glück , J. M. ; Piorkowska , Kasia ...

PLOS One , 7.
DOI: 10.1371/journal.pone.0041457


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Treatment with Aβ42 binding D-amino acid peptides reduce amyloid deposition and inflammation in APP/PS1 double transgenic mice

van Groen, Thomas; Kadish, Inga; Funke, Susanne A.; Bartnik , Dirk ...

Advances in Protein Chemistry and Structural Biology 88, 133-152.
DOI: 10.1016/B978-0-12-398314-5.00005-2


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Peptides for diagnoses and therapy of Alzheimer’s disease. Invited review, Current Pharmaceutical Design Journal, special issue "Peptides in Diagnosis and Therapy”

Funke, Susanne A.; Willbold, Dieter (2012)

Curr. Pharm. Design 18, 755-767.


Peer Reviewed

A Survey of Peptides with Effective Therapeutic Potential in Alzheimer’s Disease Rodent Models or in Human Clinical Studies

Sun, Na; Funke, Susanne A.; Willbold, Dieter (2012)

Mini-Reviews in Medicinal Chemistry 12, 5 | 388-398.
DOI: 10.2174/138955712800493942


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Staining of Amyloid Beta (Abeta) Using (Immuno) Histochemical Techniques and Abeta42 Specific Peptides.

van Groen, Thomas; Kadish, Inga; Funke, Susanne A.; Willbold, Dieter (2011)

Neuroimaging for Clinicians - Combining Research and Practice. Edited by: Julio F. P. Peres..



Prof. Dr. Susanne Funke


Hochschule Coburg

Fakultät Angewandte Naturwissenschaften und Gesundheit (FNG)
Friedrich-Streib-Str. 2
96450 Coburg

T 09561317327
aileen.funke[at]hs-coburg.de

ORCID iD: https://orcid.org/0000-0002-1160-8762